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表单
powder
质量水平
反应适用性
reagent type: cross-linking reagent
溶解性
chloroform: 50 mg/mL
DMF: soluble
acetone: soluble
储存温度
−20°C
SMILES字符串
O=C(CCSSCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O
InChI
1S/C14H16N2O8S2/c17-9-1-2-10(18)15(9)23-13(21)5-7-25-26-8-6-14(22)24-16-11(19)3-4-12(16)20/h1-8H2
InChI key
FXYPGCIGRDZWNR-UHFFFAOYSA-N
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一般描述
3,3'-二硫代二丙酸二（N-羟基琥珀酰亚胺酯）（DSP）是一种含有可裂解二硫键的同双功能交联剂。它通常在pH 7.5（6.5-8.5）的缓冲液中与含有伯胺的分子通过酰胺键发生偶联。
应用
3,3'-二硫代二丙酸二（N-羟基琥珀酰亚胺酯）（DSP）已被用作蛋白质交联剂。
特点和优势
通过温和还原，可使二硫键裂解。
注意
在偶联反应过程中避免使用还原剂。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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Vlad F
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Exposure of gold surfaces to solutions of dithiobis N-succinimidyl propionate (DTSP) gives rise to the modification of the surface with N-succinimidyl-3-thiopropionate (NSTP) which can, in turn, react with amino groups allowing for the covalent immobilization of enzymes such as horseradish
M Gamero et al.
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The design and characterization of a lactate biosensor using a nanostructured rough gold surface as a transducer is reported. The biosensor is developed by immobilization of lactate oxidase (LOx), on a rough gold electrode modified with a self-assembled monolayer of
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Journal of controlled release : official journal of the Controlled Release Society, 140(1), 40-46 (2009-07-25)
The commercially available branched polyethyleneimine (PEI) with a molar mass of 25 kD (PEI-25K) is an effective in vitro vector to transfer genes, but its cytotoxicity limits its applications in bio-related research. To solve such an efficiency-versus-cytotoxicity catch-22 problem, the
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The Analyst, 136(3), 486-492 (2010-11-17)
A bioassay platform using T4 bacteriophage (T4) as the specific receptor and surface plasmon resonance (SPR) as the transduction technique has been developed for the detection of Escherichia coli K12 bacteria. The T4 phages have been covalently immobilized onto gold
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