D2625
丹磺酰氯
BioReagent, suitable for amino acid labeling, powder and chunks, ≥99% (HPLC)
别名:
5-（二甲基氨基）-萘-1-磺酰氯, DNSCl
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关于此项目
经验公式（希尔记法）:
C12H12ClNO2S
化学文摘社编号:
分子量:
269.75
Beilstein:
2217205
EC 号:
MDL编号:
UNSPSC代码:
12352101
PubChem化学物质编号:
NACRES:
NA.26
产品线
BioReagent
质量水平
方案
≥99% (HPLC)
表单
powder and chunks
颜色
yellow to yellow-orange
mp
72-74 °C (lit.)
溶解性
acetone: 20 mg/mL
适用性
suitable for amino acid labeling
储存温度
2-8°C
SMILES字符串
CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O
InChI
1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3
InChI key
XPDXVDYUQZHFPV-UHFFFAOYSA-N
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应用
一种用于氨基酸和肽的荧光N-末端衍生化的荧光试剂，并且可用反相HPLC进行检测。
丹磺酰氯已用于：
- 用作一种荧光试剂，荧光N末端衍生化氨基酸和多肽，并通过反相高效液相色谱（HPLC）检测
- 衍生化血浆样品
- 定量固定化碱性磷酸酶
生化/生理作用
丹磺酰氯是磺酰氯化合物。它用于末端标记肽和蛋白质的氨基。丹磺酰氯用于在神经样品和生物体液中衍生游离氨基酸和胺。它用于研究白蛋白荧光复合物、蛋白质构象变化研究和活性位点鉴定。
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
WGK
WGK 3
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Simultaneous separation and quantitation of amino acids and polyamines of forest tree tissues and cell cultures within a single high-performance liquid chromatography run using dansyl derivatization
Minocha R and Long S
Journal of Chromatography A, 1035(1), 63-73 (2004)
Measuring the poise of thiol/disulfide couples in vivo
Jones DP and Liang Y
Free radical biology & medicine, 47(10), 1329-1338 (2009)
The use of dansyl-chloride for the detection of amino acids and serotonin in nervous tissue
Research Methods in Neurochemistry, 443-462 (1975)
Covalent protein immobilization on glass surfaces: Application to alkaline phosphatase
Taylor RH, et al.
Journal of Biotechnology, 118(3), 265-269 (2005)
V Konakovsky et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 28(4), 408-416 (2011-02-22)
Biogenic amines in wine may impair sensory wine quality and cause adverse health effects in susceptible individuals. In this study, histamine and other biogenic amines were determined by HPLC after amine derivatisation to dansyl chloride conjugates in 100 selected high-quality
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