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Merck
CN

D2192

Sigma-Aldrich

脱硫生物素聚氧化乙烯碘乙酰胺

≥90% (HPLC)

别名:

脱硫生物素PEO碘乙酰胺

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About This Item

经验公式(希尔记法):
C21H38IN5O6
分子量:
583.46
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:

方案

≥90% (HPLC)

表单

powder

溶解性

H2O: 10 mg/mL

储存温度

2-8°C

SMILES字符串

CC1NC(=O)NC1CCCCCC(=O)NCCC(=O)NCCOCCOCCNC(=O)CI

InChI

1S/C21H38IN5O6/c1-16-17(27-21(31)26-16)5-3-2-4-6-18(28)23-8-7-19(29)24-9-11-32-13-14-33-12-10-25-20(30)15-22/h16-17H,2-15H2,1H3,(H,23,28)(H,24,29)(H,25,30)(H2,26,27,31)

InChI key

DBOWCCSTSCXTEL-UHFFFAOYSA-N

应用

在许多蛋白质组学类型应用(如肽图和质谱)中,半胱氨酸标记尤其有用。

特点和优势

  • 在温和条件下容易从链霉亲和素或亲和素亲和基质中洗脱
  • 包含一个16原子亲水间隔区。
  • 在pH 7.5-8.5下通常与巯基偶联

其他说明

巯基特异性水溶性生物素化试剂。

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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T P Conrads et al.
Analytical chemistry, 73(9), 2132-2139 (2001-05-17)
We describe the combined use of 15N-metabolic labeling and a cysteine-reactive biotin affinity tag to isolate and quantitate cysteine-containing polypeptides (Cys-polypeptides) from Deinococcus radiodurans as well as from mouse B16 melanoma cells. D. radiodurans were cultured in both natural isotopic
Michael B Goshe et al.
Journal of proteome research, 2(2), 153-161 (2003-04-29)
The ability to identify and quantitate integral membrane proteins is an analytical challenge for mass spectrometry-based proteomics. The use of surfactants to solubilize and facilitate derivatization of these proteins can suppress peptide ionization and interfere with chromatographic separations during microcapillary
Advances in proteome analysis by mass spectrometry.
T J Griffin et al.
The Journal of biological chemistry, 276(49), 45497-45500 (2001-10-05)
Emily Turner-Brannen et al.
Arthritis research & therapy, 13(4), R129-R129 (2011-08-13)
Innate defence regulator (IDR) peptides are synthetic cationic peptides, variants of naturally occurring innate immune effector molecules known as host defence peptides. IDR peptides were recently demonstrated to limit infection-associated inflammation selectively without compromising host innate immune functions. This study

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