推荐产品
质量水平
方案
≥99%
表单
powder
储存温度
2-8°C
SMILES字符串
[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
InChI
1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
InChI key
AKUJBENLRBOFTD-RPRRAYFGSA-N
基因信息
human ... NR3C1(2908)
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应用
Dexamethasone 21-acetate has been used:
- as a component of the induction medium for the treatment of mice preadipocytes (5A) cells
- as a synthetic glucocorticoid to study its effects on the expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and peroxiredoxin 6 (Prdx6) proteins in placentas of human and mice
- as a component of the complete medium for the culturing of porcine hepatocytes
生化/生理作用
Dexamethasone 21-acetate or dexamethasone acetate is a derivative of dexamethasone. It is a hydrophobic drug. Dexamethasone is a glucocorticoid possessing anti-inflammatory activity.
警示用语：
Danger
危险声明
危险分类
Repr. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
Dexamethasone transport and ocular delivery from poly (hydroxyethyl methacrylate) gels
Kim J and Chauhan A
International Journal of Pharmaceutics, 353(1-2), 205-222 (2008)
Impact of High Fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels
Carrer1 A, et al.
The Journal of Biological Chemistry, 5(1-2), 487-487 (2017)
Culture of porcine hepatocytes or bile duct epithelial cells by inductive serum-free media
Caperna T J, et al.
In Vitro Cellular & Developmental Biology. Animal, 47(3), 218-233 (2011)
F Ceccato et al.
Journal of endocrinological investigation, 43(8), 1105-1113 (2020-02-16)
Dexamethasone Suppression Test (DST), recommended for Cushing's Syndrome (CS) diagnosis, explores the pituitary feedback to glucocorticoids. Its diagnostic accuracy could be affected by dexamethasone bioavailability, and therefore, we have developed and validated a dexamethasone threshold after 1-mg DST. We studied
Expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and peroxiredoxin 6 (Prdx6) proteins in healthy and pathologic placentas of human and rat
Acar N, et al.
Acta Histochemica, 116(8), 1289-1300 (2014)
商品
Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.
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