推荐产品
质量水平
方案
≥93%
表单
powder
SMILES字符串
[H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]6(CC[C@@H](C)CO6)O2
InChI
1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1
InChI key
WQLVFSAGQJTQCK-VKROHFNGSA-N
基因信息
human ... UGT1A4(54657)
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一般描述
薯蓣皂苷元是一种三萜类化合物，也是薯蓣皂苷的糖基衍生物。 它存在于山药、胡芦巴（Trigonella foenum-graecum）和闭鞘姜（Costus speciosus）等植物中。
应用
薯蓣皂苷元已被用于：
- 作为分析毛瓣无患子所含总皂苷的标准品
- 口服给予大鼠，以研究其对致动脉粥样化饮食诱导的心脏、肝脏和大脑炎症介质产生的抵抗作用
- 作为标准化合物，用于检测鹰嘴豆和蒺藜的皂苷含量
生化/生理作用
薯蓣皂苷元能诱导结肠癌细胞凋亡以及诱导骨肉瘤细胞的凋亡、细胞周期停滞和环加氧酶活性。它是类固醇药物生产的前体。薯蓣皂苷元已被证明能够通过刺激胆汁排泄来促进胆固醇生成。它能够影响脂氧合酶诱导的人红白血病细胞系分化。
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Chung-Hsiung Huang et al.
Journal of natural products, 73(6), 1033-1037 (2010-05-15)
It was hypothesized that the suppressive effect of diosgenin (1) on the intestinal T helper (Th)2 responses is associated with an enhancement of the regulatory T-cell immunity. Ovalbumin (OVA)-sensitized BALB/c mice were gavaged daily with 1 and received repeatedly oral
Gautam Sethi et al.
Nutrients, 10(5) (2018-05-23)
Novel and alternative options are being adopted to combat the initiation and progression of human cancers. One of the approaches is the use of molecules isolated from traditional medicinal herbs, edible dietary plants and seeds that play a pivotal role
Anuraga Jayanegara et al.
Animals : an open access journal from MDPI, 10(9) (2020-09-03)
The objective of this experiment was to test the effects of combining plant extracts rich in tannins and saponins at varying proportions on in vitro ruminal methane and ammonia formation. Tannins were extracted from Swietenia mahogani leaves and saponins from
Antioxidative and hypolipidemic effects of diosgenin, a steroidal saponin of yam (Dioscorea spp.), on high-cholesterol fed rats
Son IS, et al.
Bioscience, Biotechnology, and Biochemistry, 71(12), 3063-3071 (2007)
Fatemeh Ganjeizadeh Rohani et al.
Journal of pharmaceutical and biomedical analysis, 174, 552-560 (2019-07-01)
A novel electropolymerized molecularly imprinted polymer (MIP) film, based on diosgenin on a glassy carbon electrode (GCE), has been synthesized. Based on density functional theory (DFT), para-aminobenzoic acid (pABA), which is a green substance, was selected from five functional monomers
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