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Merck
CN

D1564

Sigma-Aldrich

Anti-DR6 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

别名:

Anti-Death Receptor 6

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About This Item

MDL编号:
UNSPSC代码:
12352203

生物来源

rabbit

偶联物

unconjugated

抗体形式

IgG fraction of antiserum

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

antigen 68 kDa

种属反应性

human

技术

microarray: suitable

UniProt登记号

运输

dry ice

储存温度

−20°C

基因信息

一般描述

DR6 is a type I transmembrane receptor and possesses four extracellular cysteine-rich motifs and a cytoplasmic death domain. It is expressed in most human tissues and its expression is found to be increased in heart, brain, placenta, pancreas, thymus, lymph node and several non-lymphoid cancer cell lines.

免疫原

synthetic peptide corresponding to amino acids 42-56 of the N-terminal region of human DR6 precursor.

外形

Solution in 0.01 M phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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G Pan et al.
FEBS letters, 431(3), 351-356 (1998-08-26)
Tumor nectosis factor (TNF) receptors are key players in inflammation and immune regulation. A new member of this family, termed death receptor-6 (DR6), has been identified. Like other death receptors, DR6 is a type I transmembrane receptor, possesses four extracellular

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