InChI key
YERHJBPPDGHCRJ-UHFFFAOYSA-N
SMILES string
C=CC(=O)N1CCN(CC1)C(=O)C=C
InChI
1S/C10H14N2O2/c1-3-9(13)11-5-7-12(8-6-11)10(14)4-2/h3-4H,1-2,5-8H2
grade
Molecular Biology
product line
BioReagent
form
powder
technique(s)
electrophoresis: suitable
mp
91.5-93.5 °C (lit.)
storage temp.
room temp
Quality Level
General description
1,4-Bis(acryloyl)piperazine is a reagent that can be substituted for bis-acrylamide in the preparation of polyacrylamide gels.
Application
Suitable for preparation of gels for PAGE, IEF, 2D electrophoresis and protein sequencing.
Features and Benefits
- increases the gel strength and resolution
- reduces background for silver background
- can be substituted for bisacrylamide without changing polymerization protocol
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Guillaume Tetreau et al.
Frontiers in immunology, 8, 1249-1249 (2017-10-21)
Detection of pathogens by all living organisms is the primary step needed to implement a coherent and efficient immune response. This implies a mediation by different soluble and/or membrane-anchored proteins related to innate immune receptors called PRRs (pattern-recognition receptors) to
Arupa Ganguly
Human mutation, 19(4), 334-342 (2002-04-05)
Conformation-sensitive gel electrophoresis (CSGE) was developed as a method of heteroduplex analysis to screen large multi-exon genes for sequence variation. The novelty of the method was in the use of a non-proprietary acrylamide gel matrix that used 1,4-bis (acrolyl) piperazine
G Artoni et al.
Analytical biochemistry, 137(2), 420-428 (1984-03-01)
The properties of gels prepared either from acryloyl-morpholine (ACM) or from its mixtures with acrylamide and crosslinked either with bisacrylylpiperazine or with methylenebisacrylamide have been described. ACM-containing gels are compatible with organic solvents. If polymerized in water and dried, they
Su-Hyung Hong et al.
Biomarker insights, 1, 175-183 (2008-09-05)
Pancreatic cancer has a poor prognosis, in part due to lack of early detection. The identification of circulating tumor antigens or their related autoantibodies provides a means for early cancer diagnosis. We have used a proteomic approach to identify proteins
D F Hochstrasser et al.
Analytical biochemistry, 173(2), 412-423 (1988-09-01)
Background staining that is associated with silver detection of proteins and nucleic acids in polyacrylamide gels has been shown to be due mostly to the amide groups in methylenebisacrylamide, a commonly used gel crosslinker. In attempts to reduce this background
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