D1068
DCB
≥98% (HPLC), solid
别名:
3,3′-二氯苯甲嗪, NSC 67224
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关于此项目
经验公式（希尔记法）:
C14H10Cl2N2
化学文摘社编号:
分子量:
277.15
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
产品名称
DCB, ≥98% (HPLC), solid
InChI
1S/C14H10Cl2N2/c15-13-5-1-3-11(7-13)9-17-18-10-12-4-2-6-14(16)8-12/h1-10H/b17-9+,18-10+
SMILES string
Clc1cccc(\C=N\N=C\c2cccc(Cl)c2)c1
InChI key
XMOVWXSCYLINBJ-BEQMOXJMSA-N
assay
≥98% (HPLC)
form
solid
storage condition
desiccated
under inert gas
color
yellow
solubility
DMSO: ~6.8 mg/mL
H2O: insoluble
storage temp.
2-8°C
Quality Level
相关类别
Biochem/physiol Actions
3,3′-二氯苯甲醛嗪（DCB）可用作具有中性协同作用的变构配体。在3,3′-二氟苯甲醛嗪（DFB）的帮助下，它可以阻断mGluRs（代谢型谷氨酸受体亚型5（mGluR5））的正向别构调节作用，以及3,3′-二甲氧基苯甲醛嗪（DMeOB）的负调节作用。
代谢型谷氨酸受体mGluR5的中性别构调节剂。
Features and Benefits
该化合物是《受体分类及信号转导》手册上谷氨酸受体（G蛋白家族）页面上的特色化合物。想要浏览手册的其他页面， 请单击此处。
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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