D0776
2′-脱氧胞苷 盐酸盐
BioReagent, suitable for cell culture
别名:
1-(2-脱氧-β-D-呋喃核糖基)胞嘧啶 盐酸盐, 2′-脱氧胞嘧啶核苷 盐酸盐
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关于此项目
经验公式（希尔记法）:
C9H13N3O4 · HCl
化学文摘社编号:
分子量:
263.68
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
EC Number:
223-639-9
Beilstein/REAXYS Number:
3576124
MDL number:
产品名称
2′-脱氧胞苷 盐酸盐, BioReagent, suitable for cell culture
InChI key
LTKCXZGFJFAPLY-OERIEOFYSA-N
InChI
1S/C9H13N3O4.ClH/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8;/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15);1H/t5-,6+,8+;/m0./s1
SMILES string
Cl[H].NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](CO)O2
biological source
synthetic
product line
BioReagent
assay
≥99% (HPLC)
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
water: 50 mg/mL, clear, colorless
Quality Level
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Application
2′-脱氧胞苷盐酸盐已用于：
- 作为基础培养基中的脱氧核糖核苷成分，研究其对莫哈韦芽孢杆菌′厌氧生长的影响
- 通过人类免疫缺陷病毒 1 型（HIV-1）对单核细胞衍生巨噬细胞的感染性测定
- 核苷补充剂，用于使人视网膜色素上皮-1（RPE-1）细胞在 G1 期同步
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Fuxia Li et al.
American journal of cancer research, 10(3), 908-924 (2020-04-09)
Epithelial ovarian cancer is characterized by universal TP53 mutations, which result in G1/S checkpoint deficiencies. Therefore, it is hypothesized that the abrogation of the G2/M checkpoint with Wee1 inhibitor might preferentially sensitize TP53-defective ovarian cancer cells. Given the extremely high
Md Maminur Rahman et al.
The Journal of biological chemistry, 295(51), 17460-17475 (2021-01-18)
Homologous recombination (HR) repairs DNA double-strand breaks using intact homologous sequences as template DNA. Broken DNA and intact homologous sequences form joint molecules (JMs), including Holliday junctions (HJs), as HR intermediates. HJs are resolved to form crossover and noncrossover products.
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Distinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFs.
Ilaria Cascone et al.
The EMBO journal, 27(18), 2375-2387 (2008-08-30)
The Ras family G-proteins RalA and RalB make critical non-overlapping contributions to the generation of a tumorigenic regulatory network, supporting bypass of the normal restraints on both cell proliferation and survival. The Sec6/8 complex, or exocyst, has emerged as a
Harry E Taylor et al.
Cell reports, 31(12), 107810-107810 (2020-06-25)
Cellular metabolism governs the susceptibility of CD4 T cells to HIV-1 infection. Multiple early post-fusion steps of HIV-1 replication are restricted in resting peripheral blood CD4 T cells; however, molecular mechanisms that underlie metabolic control of these steps remain undefined. Here, we
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