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Merck
CN

D0776

Sigma-Aldrich

2′-脱氧胞苷 盐酸盐

BioReagent, suitable for cell culture

别名:

1-(2-脱氧-β-D-呋喃核糖基)胞嘧啶 盐酸盐, 2'-脱氧胞嘧啶核苷 盐酸盐

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About This Item

经验公式(希尔记法):
C9H13N3O4 · HCl
CAS号:
分子量:
263.68
Beilstein:
3576124
EC 号:
MDL编号:
UNSPSC代码:
12352207
PubChem化学物质编号:
NACRES:
NA.75

生物来源

synthetic

质量水平

产品线

BioReagent

方案

≥99% (HPLC)

表单

powder

技术

cell culture | mammalian: suitable

溶解性

water: 50 mg/mL, clear, colorless

SMILES字符串

Cl[H].NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](CO)O2

InChI

1S/C9H13N3O4.ClH/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8;/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15);1H/t5-,6+,8+;/m0./s1

InChI key

LTKCXZGFJFAPLY-OERIEOFYSA-N

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应用

2′-脱氧胞苷盐酸盐已用于:
  • 作为基础培养基中的脱氧核糖核苷成分,研究其对莫哈韦芽孢杆菌′厌氧生长的影响
  • 通过人类免疫缺陷病毒 1 型(HIV-1)对单核细胞衍生巨噬细胞的感染性测定
  • 核苷补充剂,用于使人视网膜色素上皮-1(RPE-1)细胞在 G1 期同步

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Fuxia Li et al.
American journal of cancer research, 10(3), 908-924 (2020-04-09)
Epithelial ovarian cancer is characterized by universal TP53 mutations, which result in G1/S checkpoint deficiencies. Therefore, it is hypothesized that the abrogation of the G2/M checkpoint with Wee1 inhibitor might preferentially sensitize TP53-defective ovarian cancer cells. Given the extremely high
Md Maminur Rahman et al.
The Journal of biological chemistry, 295(51), 17460-17475 (2021-01-18)
Homologous recombination (HR) repairs DNA double-strand breaks using intact homologous sequences as template DNA. Broken DNA and intact homologous sequences form joint molecules (JMs), including Holliday junctions (HJs), as HR intermediates. HJs are resolved to form crossover and noncrossover products.
null
Ilaria Cascone et al.
The EMBO journal, 27(18), 2375-2387 (2008-08-30)
The Ras family G-proteins RalA and RalB make critical non-overlapping contributions to the generation of a tumorigenic regulatory network, supporting bypass of the normal restraints on both cell proliferation and survival. The Sec6/8 complex, or exocyst, has emerged as a
Aiman A Haqqani et al.
Virology journal, 12, 184-184 (2015-11-13)
Template switching between two distinct HIV-1 RNA genomes during reverse transcription gives rise to recombinant viruses that greatly expand the genetic diversity of HIV-1 and have adverse implications for drug resistance, immune escape, and vaccine design. Virions with two distinct

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