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表单
solid
质量水平
颜色
off-white
溶解性
H2O: moderately soluble
ethanol: soluble (Solutions should be freshly prepared.)
储存温度
2-8°C
SMILES字符串
Cl.[H][C@@]12Cc3ccc(O)c(O)c3-c4cccc(CCN1CCC)c24
InChI
1S/C19H21NO2.ClH/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14;/h3-7,15,21-22H,2,8-11H2,1H3;1H/t15-;/m0./s1
InChI key
PCOQOGIDTIFQAM-RSAXXLAASA-N
一般描述
Dissolve in oxygen-free boiled water containing 0.1% sodium metabisulfite or other antioxidant. Solutions should be freshly prepared.
生化/生理作用
Limbic-selective dopamine antagonist.
注意
Store tightly sealed at 4 °C; subject to rapid oxidation. Packed under argon; reseal bottle under argon or nitrogen to maximize stability.
警示用语：
Warning
危险声明
危险分类
STOT SE 3
靶器官
Central nervous system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
R F Cox et al.
The Journal of pharmacology and experimental therapeutics, 247(1), 355-362 (1988-10-01)
Prompted by conflicting reports of both agonist and antagonist properties of the S-(+)-enantiomer of the potent dopamine agonist R-(-)-N-n-propylnorapomorphine (NPA), we carried out extracellular, single unit recording studies to compare the effects of both enantiomers on substantia nigra and ventral
J L Neumeyer et al.
Journal of medicinal chemistry, 26(4), 516-521 (1983-04-01)
The enantiomers [(S)-(+) and (R)-(-)] of N-n-propylnorapomorphine (NPA) were synthesized. (R)-NPA was obtained by the acid-catalyzed rearrangement of N-n-propylnormorphine. (R)-NPA also was converted to (RS)-N-n-propylnorapomorphine dimethyl ether by dehydrogenation of the 10,11-O,O'-dimethyl ether of (R)-NPA with 10% palladium on carbon
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