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Merck
CN

D0400

Sigma-Aldrich

9,11-二甲氧基-9α,11α-环氧甲氧基前列腺素F

别名:

U44069

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About This Item

经验公式(希尔记法):
C21H34O4
CAS号:
分子量:
350.49
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.77

描述

solution in methyl acetate

质量水平

形式

liquid

运输

dry ice

储存温度

−20°C

SMILES字符串

CCCCC[C@H](O)\C=C\[C@H]1[C@@H]2CO[C@@H](C2)[C@@H]1C\C=C/CCCC(O)=O

InChI

1S/C21H34O4/c1-2-3-6-9-17(22)12-13-18-16-14-20(25-15-16)19(18)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16-,17-,18-,19+,20-/m0/s1

InChI key

DJKDIKIDYDXHDD-IGUVKOCZSA-N

生化/生理作用

Prostaglandin F analogue; thromboxane A2/prostaglandin H2 mimetic.

象形图

FlameExclamation mark

警示用语:

Danger

危险声明

预防措施声明

危险分类

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

靶器官

Central nervous system

补充剂危害

WGK

WGK 2

闪点(°F)

8.6 °F

闪点(°C)

-13 °C

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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M E Chapman et al.
Poultry science, 85(4), 777-786 (2006-04-18)
The pathogenesis of pulmonary hypertension remains incompletely understood. Many factors have been implicated; however, there has been great interest in the potent pulmonary vasoconstrictor serotonin (5-HT) due to episodes of primary pulmonary hypertension in humans triggered by serotoninergic appetite-suppressant drugs.
K R Olson et al.
The Journal of experimental zoology, 286(6), 606-614 (2000-04-15)
Isolated vessels from four elasmobranchs, yellow stingray (Urolophus jamaicensis), clearnose skate (Raja eglanteria), ghost shark (Hydrolagus novaezelandiae), and spiny dogfish (Squalus acanthias), were examined for the presence of spontaneous contractions (SC). SC were observed in otherwise unstimulated dorsal aortas (DA)
Zhucheng Chen et al.
Biochemistry, 42(9), 2542-2551 (2003-03-05)
Thromboxane synthase is a hemethiolate enzyme that catalyzes the isomerization of prostaglandin H2 to thromboxane A2. We report the first resonance Raman (RR) spectra of recombinant human thromboxane synthase (TXAS) in both the presence and the absence of substrate analogues
J A Scott et al.
Canadian journal of physiology and pharmacology, 77(2), 89-95 (1999-10-27)
Nonadrenergic noncholinergic (NANC) mediated vasodilation may contribute to the maintenance of low pulmonary vascular tone. The NANC neurotransmitters, nitric oxide (NO) and the sensory neuropeptides, substance P and calcitonin gene related peptide (CGRP), were investigated as possible mediators of NANC
R Scotland et al.
British journal of pharmacology, 128(6), 1229-1234 (1999-12-01)
1 The walls of certain large blood vessels are nourished by the vasa vasorum, a network of microvessels that penetrate the adventitia and media of the vessel wall. The purpose of this study was to characterize endothelin-1 (ET-1)-mediated contraction of

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