D0390
NG,NG ′-二甲基-L-精氨酸 二(对羟基偶氮苯对磺酸) 盐
≥99% (TLC)
别名:
SDMA
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关于此项目
经验公式（希尔记法）:
C8H18N4O2 · 2C12H10N2O4S
化学文摘社编号:
分子量:
758.82
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77
SMILES string
CN\C(NC)=N\CCC[C@H](N)C(O)=O.Oc1ccc(cc1)\N=N\c2ccc(cc2)S(O)(=O)=O.Oc3ccc(cc3)\N=N\c4ccc(cc4)S(O)(=O)=O
InChI
1S/2C12H10N2O4S.C8H18N4O2/c2*15-11-5-1-9(2-6-11)13-14-10-3-7-12(8-4-10)19(16,17)18;1-10-8(11-2)12-5-3-4-6(9)7(13)14/h2*1-8,15H,(H,16,17,18);6H,3-5,9H2,1-2H3,(H,13,14)(H2,10,11,12)/b2*14-13+;/t;;6-/m..0/s1
InChI key
HISUXCNNXYEHER-YJSASASGSA-N
biological source
synthetic (organic)
assay
≥99% (TLC)
form
powder
solubility
methanol: 10 mg/mL
storage temp.
room temp
Quality Level
Application
血浆 对称-二甲基精氨酸一直被认为是肝、肾功能障碍的标志。开发了用于鉴别血浆和尿液样品中精氨酸和 非对称-和 对称-二甲基精氨酸的灵敏 LC-MS 方法。
血浆 对称-二甲基精氨酸一直被认为是肝、肾功能障碍的标志。开发了用于鉴别血浆和尿液样品中精氨酸和非对称和 对称二甲基精氨酸的灵敏 LC-MS 方法。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Jane Yu et al.
Animals : an open access journal from MDPI, 10(6) (2020-06-12)
The pharmacokinetic profile of mefloquine was investigated as a preliminary study towards a potential treatment for feline coronavirus infections (such as feline infectious peritonitis) or feline calicivirus infections. Mefloquine was administered at 62.5 mg orally to seven clinically healthy cats
Lena Pelander et al.
Journal of veterinary internal medicine, 33(2), 630-639 (2019-02-23)
Early detection of decreased glomerular filtration rate (GFR) in dogs is challenging. Current methods are insensitive and new biomarkers are required. To compare overall diagnostic performance of serum symmetric dimethylarginine (SDMA) and serum cystatin C to serum creatinine, for detection
Bob Siegerink et al.
Clinical research in cardiology : official journal of the German Cardiac Society, 102(3), 193-202 (2012-10-18)
Asymmetric dimethylarginine (ADMA) is an endogenous nitric oxide synthase inhibitor, which has been associated with total and cardiovascular mortality in various clinical settings. Studies on its structural isomer, symmetric dimethylarginine (SDMA), are scarce. This study aimed to determine the associations
Xiang Gao et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 301(6), R1669-R1681 (2011-10-07)
Adenosine mediates tubuloglomerular feedback responses via activation of A(1)-receptors on the renal afferent arteriole. Increased preglomerular reactivity, due to reduced nitric oxide (NO) production or increased levels of ANG II and reactive oxygen species (ROS), has been linked to hypertension.
Olga Kruszelnicka et al.
Amino acids, 47(9), 1951-1959 (2015-04-11)
Metformin, the drug of first choice in type 2 diabetes mellitus (T2DM), reduces cardiovascular (CV) morbidity and mortality in part independently of improved glycemic control and changes in traditional risk factors. However, there are discordant reports on the effects of
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