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Merck
CN

D0250

Sigma-Aldrich

α-Dansyl-L-arginine hydrochloride

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About This Item

经验公式(希尔记法):
C18H25N5O4S · HCl
CAS号:
分子量:
443.95
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.26

方案

≥98% (TLC)

质量水平

表单

powder

颜色

yellow to green

储存温度

−20°C

SMILES字符串

CN(C)c1cccc2c(cccc12)S(=O)(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C18H25N5O4S/c1-23(2)15-9-3-7-13-12(15)6-4-10-16(13)28(26,27)22-14(17(24)25)8-5-11-21-18(19)20/h3-4,6-7,9-10,14,22H,5,8,11H2,1-2H3,(H,24,25)(H4,19,20,21)

InChI key

HRBPBWKDJGGGCX-UHFFFAOYSA-N

生化/生理作用

α-Dansyl-L-arginine contains an N-terminal fluorophore (dansyl) making it useful as fluorescent marker/probe. α-Dansyl-L-arginine is used as a site specific marker for drug binding pockets on proteins. α-Dansyl-L-arginine, dansyl-l-asparagine, and dansyl-l-glutamate are specific for the site 1 drug binding site on albumin (HSA).

象形图

Skull and crossbones

警示用语:

Danger

危险声明

预防措施声明

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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J M Mesaros et al.
Analytical chemistry, 68(19), 3441-3449 (1996-10-01)
Continuous zone electrophoretic separations in narrow channels coupled to small-bore capillaries have been demonstrated and characterized previously. Presented here is the use of this new technique to monitor dynamic chemical changes occurring in a flow injection analysis system. The fundamental
P J McIlroy et al.
Endocrinology, 113(1), 222-227 (1983-07-01)
The effects of dansyl-arginyl-(4'-ethyl)-piperidine amide (DAPA) on the binding of gonadotropins has been investigated. The compound inhibited the binding of hCG, human LH, and porcine LH to rat luteal membranes with an ED50 of 70 microM and the binding of
N Muller et al.
The Journal of pharmacy and pharmacology, 46(4), 300-304 (1994-04-01)
Human serum albumin is known to have two major and selective drug binding sites, termed sites I and II. The fluorescent probes, dansylamide and dansylsarcosine selectively interact with sites I and II, respectively. However, the binding site of the fluorescent
Ali J Ryan et al.
Journal of structural biology, 174(1), 84-91 (2010-10-14)
Human serum albumin (HSA) has two primary binding sites for drug molecules. These sites selectively bind different dansylated amino acid compounds, which-due to their intrinsic fluorescence-have long been used as specific markers for the drug pockets on HSA. We present

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