产品名称
β-N-乙酰氨基葡萄糖苷酶检测试剂盒, sufficient for 50 reactions (1 mL), sufficient for 500 reactions (100 μL)
usage
sufficient for 50 reactions (1 mL)
sufficient for 500 reactions (100 μL)
shipped in
wet ice
storage temp.
2-8°C
Quality Level
Gene Information
human ... NAGLU(4669)
Analysis Note
该试剂盒的检测原理为NAG（NP-GLcNAc）底物在酶促作用下水解。酶水解底物后，释放出对硝基苯胺离子。然后在405 nm处采用比色法测定反应产物。
Application
该试剂盒可在细胞溶解液、组织匀浆或纯化酶等样品中方便、快速地检测β-N-乙酰氨基葡萄糖苷酶。它是一种理想的分离细胞/组织样品溶酶体检测工具。
Biochem/physiol Actions
哺乳类动物体内的N-乙酰-D-氨基葡萄糖苷酶 (NAG) 是一种参与胞内糖脂和糖蛋白降解的溶酶体酶。在人类肾脏、肺和肝脏溶酶体中都已检测到高活性的NAG。血清NAG水平升高与某些癌症有关。
signalword
Warning
hcodes
Hazard Classifications
Carc. 2 - Eye Irrit. 2 - STOT RE 2 Oral
target_organs
Liver,Kidney
存储类别
11 - Combustible Solids
法规信息
易制毒化学品（2类）
含少量动物源组分生物产品
此项目有
Shanshan Wang et al.
Biochemical and biophysical research communications, 483(1), 45-51 (2017-01-09)
Activation of endothelial cells plays a key role in septic acute kidney injury (AKI). This study investigated the role of miRNA in endothelial-induced tubular cell injury in sepsis. Circulating endothelial cells (CECs) from septic AKI, non-septic AKI, septic non-AKI patients
Na Zhang et al.
Cell death & disease, 9(2), 230-230 (2018-02-16)
Glycogen synthase kinase-3β (GSK-3β) is a ubiquitously expressed serine/threonine kinase involved in a variety of functions ranging from the control of glycogen metabolism to transcriptional regulation. We recently demonstrated that GSK-3β inhibition triggered ASK1-JNK-dependent apoptosis in human hepatocellular carcinoma (HCC)
Qiuyuan Yin et al.
The Journal of cell biology, 219(8) (2020-07-15)
Lysosomes are degradation and signaling organelles that adapt their biogenesis to meet many different cellular demands; however, it is unknown how lysosomes change their numbers for cell division. Here, we report that the cyclin-dependent kinases CDK4/6 regulate lysosome biogenesis during
Miguel A Lanaspa et al.
Journal of the American Society of Nephrology : JASN, 25(11), 2526-2538 (2014-05-31)
Diabetes is associated with activation of the polyol pathway, in which glucose is converted to sorbitol by aldose reductase. Previous studies focused on the role of sorbitol in mediating diabetic complications. However, in the proximal tubule, sorbitol can be converted
Xiaoting Chen et al.
Journal of cellular and molecular medicine, 23(6), 4290-4300 (2019-04-12)
Impaired autophagic degradation of intracellular lipids is causally linked to the development of non-alcoholic steatohepatitis (NASH). Pharmacological agents that can restore hepatic autophagic flux could therefore have therapeutic potentials for this increasingly prevalent disease. Herein, we investigated the effects of
商品
Centrifugation separates organelles based on size, shape, and density, facilitating subcellular fractionation across various samples.
亚细胞组分离心分离是一种常用技术，广泛适用于多种类型的细胞和组织。由于不同细胞器的大小、形状和密度不同，因此通过离心，可从温和均质的样品中轻松分离和纯化细胞器组分。
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持