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Merck
CN
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文件

安全信息

C9858

Sigma-Aldrich

肌酸激酶 MM 组分 来源于人类心脏

lyophilized powder

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MDL编号:
MFCD00151687
UNSPSC代码:
12352204
eCl@ss:
32160410
NACRES:
NA.54

形式

lyophilized powder

质量水平

200

比活

≥100 units/mg protein

UniProt登记号

P06732

储存温度

−20°C

基因信息

human ... CKM(1158)

特异性

一个单元将在 37℃ 下每分钟将1.0μmol磷酸盐从磷酸肌酸传输 ADP（在 340 nm 处测量，以偶联反应产生 1 等摩尔量的 NADH 计）。

应用

来自人类心脏的肌酸激酶 MM 组分已被用于一项研究，以探讨术中和术后心脏药物治疗在急性心肌梗死急诊冠状动脉旁路移植术中的重要性。来自人心脏的肌酸激酶 MM 组分也被用于研究 ST 段抬高心肌梗死后梗死面积和左心室功能的昼夜节律依赖性。

生化/生理作用

在监测心肌损伤时可作为质控品或校准品。

警告

所有人源材料的 HIV1、HIV2、HCV 抗体和 HbsAg 检测结果均为阴性。无测试保证产品无传染性。因此，所有来源于人体体液或组织的材料均应视为具有潜在传染性。

单位定义

在37°C条件下，一个单位每分钟可以将1.0 微摩尔磷酸盐从磷酸肌酸转移至ADP。

外形

含 Tris-HCl、EDTA 和 N-乙酰半胱氨酸的冻干粉。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What does the MM stand for in Product C9858, Creatine Kinase MM Fraction from human heart?

    Creatine Kinase is a dimer that exists as three isozymes: MM (muscle), MB (hybrid) and BB (brain).

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Akira Sato et al.
Journal of the American College of Cardiology, 59(8), 730-738 (2012-02-22)
This study evaluated the clinical value of myocardial contrast delayed enhancement (DE) with multidetector computed tomography (MDCT) for predicting clinical outcome after acute myocardial infarction (AMI). Although some studies have described the use of MDCT for assessment of myocardial viability
Akira Sezai et al.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 18(4), 338-346 (2012-05-11)
The results of emergency coronary artery bypass grafting (CABG) for acute myocardial infarction (AMI) are less than satisfactory, and readmission for cardiac events is common. 105 patients underwent emergency CABG for AMI. We examined the long-term results of emergency CABG
Ronald Reiter et al.
Circulation research, 110(1), 105-110 (2011-11-19)
In rodents, infarct size after ischemia/reperfusion exhibits a circadian dependence on the time of coronary occlusion. It is not known if a similar circadian dependence of infarct size occurs in humans. To determine if humans exhibit a circadian dependence of
Helen Lee et al.
The European journal of neuroscience, 31(8), 1388-1401 (2010-04-14)
Horizontal cells are lateral interneurons that participate in visual processing in the outer retina but the cellular mechanisms underlying transmitter release from these cells are not fully understood. In non-mammalian horizontal cells, GABA release has been shown to occur by

Chromatograms

application for HPLC

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