推荐产品
一般描述
人补体血清标准品适用于测定 CH50 和 AP50 补体活性。这让我们可以对血清在体外裂解红细胞能力的补体活性进行测试，并可用于对补体系统的 DNA 样品进行基因分型的操作程序。
应用
人补体血清标准品已用作阳性对照品，研究补体系统在哺乳动物脊髓免疫脱髓鞘中的作用。
生化/生理作用
补体系统是天然免疫的重要组成部分。它是抵御微生物感染、改变宿主细胞以及清除免疫复合物和受伤细胞的第一道防线。补体系统包括肝脏产生的血浆蛋白、细胞表面表达的膜蛋白、细胞因子和激素等三十多种组分。补体蛋白组合起来调整病原体，并启动一系列炎症反应，协助免疫细胞对抗感染并维持稳态。
外形
以含 18 mM左右柠檬酸盐l、22 m左右葡萄糖、3 mM左右磷酸盐和13 mM钙的0.22 μm过滤溶液形式提供。
免责声明
仅供研究使用。本品在法国的科研应用受到监管，包括用于进口和出口活动（法国《公共卫生法典》Public Health Code Article L 1211-1 paragraph 2）。如《公共卫生法典》所述，购买者（即最终用户）需要从法国研究部(France Ministry of Research)获得进口授权。订购此产品即代表您已确认获得合法的进口授权。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
高风险级别生物产品--人源产品
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Specificity of serum complement component to elicit immunological demyelination. To assess the role of complement components and pathways in experimental immunological demyelination of the adult rat spinal cord. ICORD, University of British Columbia, Vancouver, Canada. We used 32 adult male
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Complement is an important component of the innate immune system that is crucial for defense from microbial infections and for clearance of immune complexes and injured cells. In normal conditions complement is tightly controlled by a number of fluid-phase and
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Nicolas S Merle et al.
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Complement is a complex innate immune surveillance system, playing a key role in defense against pathogens and in host homeostasis. The complement system is initiated by conformational changes in recognition molecular complexes upon sensing danger signals. The subsequent cascade of
P J Francis et al.
Journal of medical genetics, 46(5), 300-307 (2008-11-19)
Age related macular degeneration (AMD) is a leading cause of blindness. AMD is a complex disorder caused by genetic and environmental factors in which single nucleotide polymorphisms (SNPs) in the genes CFH and LOC387715/HTRA1/ARMS2 have prognostic importance for progression to
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