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Merck
CN
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文件

C9394

Sigma-Aldrich

氯己定 二葡糖酸盐 溶液

20% in H2O

别名:

1,6-双（N5-[对氯苯基]-N1-双胍）己烷；1,1′-六亚甲基双（5-[对氯苯基]双胍）

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About This Item

CAS号:
18472-51-0
MDL编号:
MFCD00083599
UNSPSC代码:
51101500
PubChem化学物质编号:
329775206
NACRES:
NA.85

形式

liquid

质量水平

200

浓度

20% in H2O

溶解性

water: soluble 50 % (w/v)

密度

1.06 g/mL at 25 °C (lit.)

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

作用机制

cell membrane | interferes

储存温度

2-8°C

SMILES字符串

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

InChI

1S/C22H30Cl2N10.2C6H12O7/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*7-1-2(8)3(9)4(10)5(11)6(12)13/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*2-5,7-11H,1H2,(H,12,13)/t;2*2-,3-,4+,5-/m.11/s1

InChI key

YZIYKJHYYHPJIB-UUPCJSQJSA-N

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相关类别

应用

可用于研究双（双胍）分子破坏膜的作用机制。
氯己定已被用于研究精油与氯己定二葡糖酸盐联合使用时，如何改善皮肤消毒效果 ，并可用于皮肤渗透研究 。 用氯己定慢性冲洗已经证明可以降低NaCl的咸味和奎宁的苦味。

生化/生理作用

阳离子广谱抗菌剂属于双（双胍）家族。 其作用机制涉及破坏外部细菌膜稳定性。 它主要用作伤口愈合、导管插入部位、各种牙科应用和手术擦洗中的局部抗菌/消毒剂。

其他说明

保持容器密闭，并置于干燥通风处。打开后的容器必须小心重新密封并保持直立以防止泄漏。光敏感。

相关产品

产品编号
说明
价格

象形图

CorrosionEnvironment
GHS05,GHS09

警示用语：

Danger

危险声明

H318,H410

危险分类

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)

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