推荐产品
生物来源
synthetic
质量水平
检测方案
≥98% (TLC)
形式
powder
mp
205 °C
溶解性
water: 50 mg/mL, clear, colorless
储存温度
−20°C
SMILES字符串
Cl[H].N[C@@H](CCl)C(O)=O
InChI
1S/C3H6ClNO2.ClH/c4-1-2(5)3(6)7;/h2H,1,5H2,(H,6,7);1H/t2-;/m0./s1
InChI key
IENJPSDBNBGIEL-DKWTVANSSA-N
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应用
ββ-氯-L-丙氨酸盐酸盐已用于：
- 作为底物，用于研究酪氨酸酚裂解酶稳态动力学
- 研究Ly-1淋巴细胞中的丝氨酸棕榈酰转移酶抑制和细胞毒性
- 在小麦胚无细胞蛋白合成系统中作为丙氨酸转氨酶抑制剂
生化/生理作用
ββ-氯-L-丙氨酸盐酸盐是丙氨酸氨基转移酶(ALAT)抑制剂。抑制ALAT可导致肺癌进展抑制。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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Hanada K, et al.
Biochemical Pharmacology, 59(10), 1211-1216 (2000)
Inhibition of alanine aminotransferase (ALAT) in silico and in vivo promotes mitochondrial metabolism to impair malignant growth
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A novel way of amino acid-specific assignment in 1 H-15 N HSQC spectra with a wheat germ cell-free protein synthesis system
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Affinity labeling of alanine aminotransferase by 3-chloro-L-alanine.
Y Morino et al.
The Journal of biological chemistry, 254(2), 279-285 (1979-01-25)
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