C8003
5α-胆甾烷溶液
≥97.0% (HPLC)
别名:
NSC 224419
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关于此项目
经验公式（希尔记法）:
C27H48
化学文摘社编号:
分子量:
372.67
UNSPSC Code:
12352211
NACRES:
NA.77
PubChem Substance ID:
EC Number:
207-562-8
Beilstein/REAXYS Number:
2051806
MDL number:
产品名称
5α-胆甾烷溶液, ≥97.0% (HPLC)
InChI key
XIIAYQZJNBULGD-XWLABEFZSA-N
InChI
1S/C27H48/c1-19(2)9-8-10-20(3)23-14-15-24-22-13-12-21-11-6-7-17-26(21,4)25(22)16-18-27(23,24)5/h19-25H,6-18H2,1-5H3/t20-,21-,22+,23-,24+,25+,26+,27-/m1/s1
SMILES string
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4CCCC[C@]4(C)[C@H]3CC[C@]12C
assay
≥97.0% (HPLC)
form
powder
mp
80-82 °C (lit.)
Quality Level
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Application
5-α-胆甾烷已用于：
- 作为气相色谱（GC）和高效液相色谱（HPLC）的内标，用于定量肉制品中的胆固醇，从而进行比较研究
- 通过质谱和气相色谱联用对油中的活性化合物进行定量分析
- 作为 GC 分析中的参考标准，对从燕麦脂质和不同甾醇标准品（如岩藻甾醇、谷甾醇、樟脑甾醇和豆甾醇）中获得的不皂化物中的甾醇进行定量分析
Biochem/physiol Actions
5α-胆甾烷是一种胆固醇内生甾醇，从人类粪便中分离得到。它是肠道微生物作用于胆固醇而产生的。植物中的5α-胆甾烷衍生物被称为油菜素类固醇，可选择性激活 PPI3K/Akt 途径。
Preparation Note
50 mg/ml的5α-胆甾烷氯仿溶液澄清至略微混浊，无色至淡黄色。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Angelisa T Y Osmond et al.
Animals : an open access journal from MDPI, 11(4) (2021-05-01)
In this study, we evaluated whether oil extracted from the marine microbe, Schizochytrium sp. (strain T18), with high levels of docosahexaenoic acid (DHA), could replace fish oil (FO) in diets for rainbow trout (Oncorhynchus mykiss). Three experimental diets were tested:
L J Chen et al.
Journal of agricultural and food chemistry, 58(19), 10467-10474 (2010-09-11)
The objectives of this study were to develop a GC-MS method for determination of cholesterol oxidation products (COPs) in tea-leaf eggs and study the formation and inhibition of COPs as affected by heating time and various ingredients in marinated juice.
Comparative Analysis and Validation Methodologies of GC and HPLC for Analysis of Cholesterol in Meat Products
Stroher GL et al
American Journal of Analytical Chemistry, 3, 306-311 (2012)
Abdulaziz A Alaqil et al.
Animals : an open access journal from MDPI, 10(9) (2020-09-10)
This study examines the effect of dietary supplementation with Lactobacillus acidophilus (LA) on the cholesterol levels, immune response, and productive performance of laying hens. A total of 216, 40-week-old, commercial Hy-Line brown chicken layers were randomly assigned into four treatment
Stefanie M Hixson et al.
PloS one, 11(3), e0152264-e0152264 (2016-03-25)
Nutritional enhancement of crops using genetic engineering can potentially affect herbivorous pests. Recently, oilseed crops have been genetically engineered to produce the long-chain omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) at levels similar to that found
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