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Merck
CN
所有图片(1)

主要文件

C7956

Sigma-Aldrich

辅酶Q1

≥95%

别名:

2,3-二甲氧基-5-甲基-6-(3-甲基-2-丁烯基)-1,4-苯醌, 泛醌-1, 泛醌-5

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About This Item

经验公式(希尔记法):
C14H18O4
CAS号:
分子量:
250.29
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.51

质量水平

方案

≥95%

表单

liquid

储存温度

−20°C

SMILES字符串

COC1=C(OC)C(=O)C(C\C=C(\C)C)=C(C)C1=O

InChI

1S/C14H18O4/c1-8(2)6-7-10-9(3)11(15)13(17-4)14(18-5)12(10)16/h6H,7H2,1-5H3

InChI key

SOECUQMRSRVZQQ-UHFFFAOYSA-N

一般描述

辅酶Q(CoQ)位于线粒体磷脂双层膜、血浆脂蛋白和其他生物膜的疏水区域。是带有短的类萜侧链的泛醌同系物。

应用

辅酶Q1已用于检测线粒体呼吸链复合物1的活性。

生化/生理作用

辅酶Q1(CoQ1)是泛醌家族的1异戊烯基成员(非天然),这些泛醌均有一个奎宁化学基团,但尾部异戊烯基化学亚基的数量不同。 辅酶Q类化合物是细胞膜的脂溶性组分,可以行使多种功能,例如电子和质子传递。 研究最充分的辅酶Q类化合物是辅酶Q10(CoQ10)。 CoQ1常在比较研究中用于探索不同异戊烯链长对CoQ功能或分布的影响,还可用于醌还原酶的鉴定。

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Nandita Shangari et al.
Methods in enzymology, 400, 342-359 (2006-01-10)
Phase II conjugation of phenolic compounds constitutes an important mechanism through which exogenous or endogenous toxins are detoxified and excreted. Species differences in the rates of glucuronidation or sulfation can lead to significant variation in the metabolism of this class
C Edlund et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 70(6), 422-428 (1992-06-01)
The lipid compositions of various regions of the human brain were investigated during aging and in Alzheimer's disease. The phospholipid amounts and compositions remained unchanged during aging. There were, however, considerable differences both in phospholipid composition and amount when the
Chang Sun et al.
Nature, 557(7703), 123-126 (2018-04-27)
Alternative complex III (ACIII) is a key component of the respiratory and/or photosynthetic electron transport chains of many bacteria1-3. Like complex III (also known as the bc1 complex), ACIII catalyses the oxidation of membrane-bound quinol and the reduction of cytochrome
Kathrin Fenn et al.
Microbiome, 5(1), 161-161 (2017-12-22)
The human gut microbiome has been linked to numerous components of health and disease. However, approximately 25% of the bacterial species in the gut remain uncultured, which limits our ability to properly understand, and exploit, the human microbiome. Previously, we
Coenzyme Q cytoprotective mechanisms.
Tom S Chan et al.
Methods in enzymology, 382, 89-104 (2004-03-30)

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