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安全和法规

C7927

Cecropin P1 Porcine

Name: Cecropin P1 Porcine
Brand: SIGMA

≥95% (HPLC), powder

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About This Item

经验公式（希尔记法）:

C₁₄₇H₂₅₃N₄₅O₄₃

CAS号:

125667-96-1

分子量:

3338.86

MDL编号:

MFCD00079839

UNSPSC代码:

12352200

PubChem化学物质编号:

24892582

NACRES:

NA.32

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Sigma-Aldrich

C1000

乙酸钙水合物

Sigma-Aldrich

72779

三氯生

Sigma-Aldrich

C1796

Cecropin B

Sigma-Aldrich

C6830

抗菌肽A

Sigma-Aldrich

H3393

肝素钠盐来源于猪肠粘膜

Sigma-Aldrich

D9565

β-Defensin 1 human

Sigma-Aldrich

105937

3,4,4′-三氯二苯脲

Sigma-Aldrich

N8630

核酸酶P₁ 来源于桔青霉菌

Sigma-Aldrich

M2272

蜂毒肽来源蜜蜂毒液

Sigma-Aldrich

I4883

布洛芬

质量水平

200

方案

≥95% (HPLC)

表单

powder

抗生素抗菌谱

fungi

作用机制

cell membrane | interferes

储存温度

−20°C

SMILES字符串

CCC(C)C(NC(=O)CNC(=O)C(CCC(O)=O)NC(=O)C(CO)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(N)CO)C(C)O)C(C)CC)C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NCC(=O)NCC(=O)N3CCCC3C(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C147H253N45O43/c1-18-75(9)113(140(229)167-81(15)120(209)188-114(76(10)19-2)141(230)168-82(16)121(210)189-115(77(11)20-3)142(231)178-94(47-50-106(154)198)123(212)164-66-108(200)163-68-110(202)192-60-36-46-105(192)139(228)179-97(145(234)235)45-35-59-161-147(158)159)187-109(201)67-165-124(213)95(48-51-111(203)204)176-138(227)104(72-196)186-143(232)116(78(12)21-4)190-130(219)93(44-34-58-160-146(156)157)174-127(216)90(41-26-31-55-150)172-125(214)88(39-24-29-53-148)170-118(207)79(13)166-136(225)102(70-194)184-135(224)101(64-107(155)199)183-129(218)96(49-52-112(205)206)177-132(221)98(61-73(5)6)181-128(217)91(42-27-32-56-151)173-126(215)89(40-25-30-54-149)171-119(208)80(14)169-144(233)117(83(17)197)191-131(220)92(43-28-33-57-152)175-137(226)103(71-195)185-133(222)99(62-74(7)8)182-134(223)100(180-122(211)86(153)69-193)63-84-65-162-87-38-23-22-37-85(84)87/h22-23,37-38,65,73-83,86,88-105,113-117,162,193-197H,18-21,24-36,39-64,66-72,148-153H2,1-17H3,(H2,154,198)(H2,155,199)(H,163,200)(H,164,212)(H,165,213)(H,166,225)(H,167,229)(H,168,230)(H,169,233)(H,170,207)(H,171,208)(H,172,214)(H,173,215)(H,174,216)(H,175,226)(H,176,227)(H,177,221)(H,178,231)(H,179,228)(H,180,211)(H,181,217)(H,182,223)(H,183,218)(H,184,224)(H,185,222)(H,186,232)(H,187,201)(H,188,209)(H,189,210)(H,190,219)(H,191,220)(H,203,204)(H,205,206)(H,234,235)(H4,156,157,160)(H4,158,159,161)

InChI key

PRIVBYDFWSFUFP-UHFFFAOYSA-N

Amino Acid Sequence

Ser-Trp-Leu-Ser-Lys-Thr-Ala-Lys-Lys-Leu-Glu-Asn-Ser-Ala-Lys-Lys-Arg-Ile-Ser-Glu-Gly-Ile-Ala-Ile-Ala-Ile-Gln-Gly-Gly-Pro-Arg

一般描述

Cecropin P1 is found in Ascaris suum, which is a parasite that lives in porcine intestine.

应用

Cecropin P1 Porcine has been used to study its antimicrobial activity against Escherichia coli.

生化/生理作用

Antibacterial peptide originally identified in moths (Hyalophora cecropia) and later in pig intestine.

Cecropin P1 can inhibit the growth of enterotoxigenic Escherichia coli in porcine. It also can inhibit the growth of human fungal pathogen Candida albicans. Cecropin P1 also blocks the release of viral particles and impairs virus-induced apoptosis. Cecropins are cationic anti-microbial peptides (AMPs). It can inactivate microorganisms by forming an α-helical chain which punctures the cell membrane. Cecropins may be used in food preservation as it is non-cytotoxic to mammalian cells.

免责声明

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Insect antimicrobial peptides, a mini review

Wu Q, et al.

Toxins, 10(11), 461-461 (2018)

Natural antimicrobial agents to improve foods shelf life

Food quality and safety, 172(3), 125-157 (2019)

Discovery of next-generation antimicrobials through bacterial self-screening of surface-displayed peptide libraries

Tucker A T, et al.

Cell, 172(3), 618-628 (2018)

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主要文件

安全信息

Cecropin P1 Porcine

≥95% (HPLC), powder

About This Item

推荐产品

属性

质量水平

方案

表单

抗生素抗菌谱

作用机制

储存温度

SMILES字符串

InChI

InChI key

说明

Amino Acid Sequence

一般描述

应用

生化/生理作用

免责声明

安全信息

储存分类代码

WGK

闪点(°F)

闪点(°C)

个人防护装备

法规信息

文件

分析证书(COA)

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