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Merck
CN

C7527

Sigma-Aldrich

氯化胆碱

BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98%

别名:

(2-羟乙基)三甲基氯化铵

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About This Item

线性分子式:
(CH3)3N(Cl)CH2CH2OH
CAS号:
分子量:
139.62
Beilstein:
3563126
EC 号:
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.75

生物来源

synthetic (organic)

质量水平

产品线

BioReagent

检测方案

≥98%

形式

crystals

分子量

Mw 139.62 g/mol

技术

cell culture | insect: suitable
cell culture | mammalian: suitable
cell culture | plant: suitable

颜色

white

pH值(酸碱度)

5.0-6.5 (25 °C, 140 g/L)

mp

302-305 °C (dec.) (lit.)

溶解性

H2O: 50 mg/mL

SMILES字符串

[Cl-].C[N+](C)(C)CCO

InChI

1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1

InChI key

SGMZJAMFUVOLNK-UHFFFAOYSA-M

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一般描述

氯化胆碱是一种季铵盐,与氢键供体(HBD)缔合。它是许多重要生理功能必不可少的成分,用作营养添加剂。胆碱是甲基转移反应的甲基来源。

应用

氯化胆碱已用于:
  • 用作胆碱乙酰基转移酶 (ChAT)缓冲液组分,用于培养人成神经细胞瘤(SK-N-SH)细胞中的胆碱吸收
  • 生成胆碱标准曲线,以定量磷脂酶D (PLD)活性
  • 用作解剖内海马脑切片的切片溶液组分

底物

胆碱乙酰基转移酶底物

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Zeisel SH and Da Costa KA
Nutr. Rev, 67(11), 615-623 (2009)
Harvie P Portugaliza et al.
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Transmission of malaria parasites from humans to mosquito vectors requires that some asexual parasites differentiate into sexual forms termed gametocytes. The balance between proliferation in the same host and conversion into transmission forms can be altered by the conditions of
Synthesis and characterization of choline chloride based binary mixtures
Abbas Q and Binder L
ECS Transactions, 33(7), 49-59 (2010)
Apoptosis of bovine granulosa cells: Intracellular pathways and differentiation
Carou MC, et al.
Acta Histochemica, 119(5), 462-470 (2017)
Zhenglin Gu et al.
Cell reports, 31(10), 107740-107740 (2020-06-11)
Muscarinic acetylcholine receptors (mAChRs) are critically involved in hippocampal theta generation, but much less is known about the role of nicotinic AChRs (nAChRs). Here we provide evidence that α7 nAChRs expressed on interneurons, particularly those in oriens lacunosum moleculare (OLM)

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