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应用
环磷酰胺是氮芥类烷化剂,被广泛用于抗肿瘤和抗免疫药物的作用机理研究。
生化/生理作用
广泛用于癌症化疗的细胞毒性氮芥衍生物。它可与 DNA 交联、导致链断裂并诱导突变。
环磷酰胺是一种广泛用于癌症化疗的具有细胞毒性的氮芥衍生物。它可与 DNA 交联、导致链断裂并诱导突变。其临床活性与乙醛脱氢酶 1 (ALDH1) 的活性降低相关。
包装
包装在 100 mL 血清瓶中,具有硅/PTFE 隔膜和铝封。
注意
将相容溶剂直接注入小瓶中,可制备任何所需规格的溶液,无需暴露。
重悬
将内容物溶于 100 mL 溶剂中,得到 1% 溶液。
法律信息
Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany
ISOPAC
产品编号
说明
价格
警示用语:
Danger
危险分类
Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Allogeneic hematopoietic stem cell transplantation (alloSCT) is a potentially curative therapy for many hematologic and immunologic diseases. Further, partial or full donor hematopoietic chimerism following alloSCT may be sufficient to guarantee immunologic tolerance to solid organs from the same donor
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