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Merck
CN

C7397

Sigma-Aldrich

环磷酰胺 一水合物

ISOPAC®

别名:

2-[双(2-氯乙基)氨基]四氢-2H-1,3,2-噁磷-2-氧化物, Cytoxan

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About This Item

经验公式(希尔记法):
C7H15Cl2N2O2P · H2O
CAS号:
分子量:
279.10
Beilstein:
4678992
EC 号:
MDL编号:
UNSPSC代码:
51112507
PubChem化学物质编号:
NACRES:
NA.25

质量水平

方案

97.0-103.0% (HPLC)

表单

powder

mp

49-51 °C (lit.)

储存温度

2-8°C

SMILES字符串

[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1

InChI

1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

InChI key

PWOQRKCAHTVFLB-UHFFFAOYSA-N

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应用

环磷酰胺是氮芥类烷化剂,被广泛用于抗肿瘤和抗免疫药物的作用机理研究。

生化/生理作用

广泛用于癌症化疗的细胞毒性氮芥衍生物。它可与 DNA 交联、导致链断裂并诱导突变。
环磷酰胺是一种广泛用于癌症化疗的具有细胞毒性的氮芥衍生物。它可与 DNA 交联、导致链断裂并诱导突变。其临床活性与乙醛脱氢酶 1 (ALDH1) 的活性降低相关。

包装

包装在 100 mL 血清瓶中,具有硅/PTFE 隔膜和铝封。

注意

将相容溶剂直接注入小瓶中,可制备任何所需规格的溶液,无需暴露。

重悬

将内容物溶于 100 mL 溶剂中,得到 1% 溶液。

法律信息

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

ISOPAC

产品编号
说明
价格

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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