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生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
49801.111, monoclonal
形式
lyophilized powder
种属反应性
human
技术
flow cytometry: suitable
同位素/亚型
IgG1
UniProt登记号
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... CXCR3(2833)
mouse ... Cxcr3(12766)
相关类别
一般描述
Chemokine receptor CXCR3 also refers as IP -10 or Mig receptor is a Gαi protein-coupled receptor and is highly expressed by IL-2-activated T lymphocytes (Th1). It facilitates calcium mobilization and chemotaxis. It also plays a pivotal role in wound healing. Monoclonal Anti-CXCR3 antibody can be used in flow cytometry for the Identification of CXCR-3. Mouse anti-CXCR3 antibody reacts specifically with CXCR-3 transfected cells but not with the parent cell line. The product has shown no cross-reactivity with human CXCR-1, CXCR-2 and CXCR-4.
特异性
The antibody reacts with human CXCR3 transfectant cells and not the parent cell line. It has no cross-reactivity with CXCR1, CXCR2, or CXCR4.
免疫原
human CXCR3 transfected NSO mouse myeloma cells.
应用
Monoclonal Anti-CXCR3 antibody can be used as a positive control in immunohistochemical staining.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
制备说明
Purified using protein G.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Anja Mueller et al.
Journal of leukocyte biology, 83(4), 875-882 (2008-01-05)
The chemokine CXCL4/platelet factor-4 is released by activated platelets in micromolar concentrations and is a chemoattractant for leukocytes via an unidentified receptor. Recently, a variant of the human chemokine receptor CXCR3 (CXCR3-B) was described, which transduced apoptotic but not chemotactic
Cecelia C Yates et al.
The American journal of pathology, 171(2), 484-495 (2007-06-30)
Replacement of wounded skin requires the initially florid cellular response to abate and even regress as the dermal layer returns to a relatively paucicellular state. The signals that direct this "stop and return" process have yet to be deciphered. CXCR3
S Kobayashi et al.
Rheumatology (Oxford, England), 47(9), 1317-1322 (2008-07-12)
Environmental factors are involved in RA pathogenesis and epidemiological studies have suggested that smoking is an environmental risk factor for RA. The 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is one of the major toxic components in cigarettes. To clarify the biological effects of smoking
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