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Merck
CN

C6277

Sigma-Aldrich

刚果红

Dye content, ≥85%, certified by the Biological Stain Commission, powder

别名:

刚果红 4B, 棉红 B, 棉红 C, 煮大红, 直接红 28, 直接红 R, 直接红 Y

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About This Item

经验公式(希尔记法):
C32H22N6Na2O6S2
CAS号:
分子量:
696.66
颜色索引号:
22120
Beilstein:
3894858
EC 号:
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47

product name

刚果红, BioXtra, certified by the Biological Stain Commission

等级

certified by the Biological Stain Commission

质量水平

产品线

BioXtra

形式

powder

组成

Dye content, ≥85%

mp

>360 °C (lit.)

溶解性

H2O: 10 mg/mL

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

[Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c3ccc(cc3)-c4ccc(cc4)\N=N\c5cc(c6ccccc6c5N)S([O-])(=O)=O

InChI

1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;;

InChI key

IQFVPQOLBLOTPF-HKXUKFGYSA-L

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应用

刚果红已可用于β淀粉样肽的染色。

生化/生理作用

刚果红是一种基于联苯胺的阴离子重氮染料。它是一种组织学染料,可与多种淀粉样蛋白结合,用于定量淀粉样蛋白β-肽聚集。刚果红还能与β-D-葡聚糖、含有连续β-(1→4)-键的D-吡喃葡萄糖基单元的多糖以及一些半纤维素半乳糖甘露聚糖发生相互作用。

适用性

经认证可用作明矾苏木精的复染剂,以及用于Puchtler淀粉样蛋白染色的Highman或Churukian修饰。

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Carc. 1B - Repr. 2

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


分析证书(COA)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Why does the SDS for Congo Red list carcinogen as an OSHA hazard, (Section 2) but in Section 11 on carcinogenicity, it states that there is no component identified as a carcinogen?

    The reason that there is not an OSHA listing for carcinogens on most of SDS that have a hazard of a carcinogen hazard is because that section of the SDS is specifically for the OSHA regulated carcinogens, also referred to as the OSHA 13. Congo red at this time is not specifically called out  as a carcinogen by the other 3 Organizations listed (IARC, NTP, ACGIH) either. Congo red is listed by the European Classification Labeling & Packaging (CLP) Regulation (which is a pretty definitive guide for hazard classification), as a carcinogen. No other organizations have had the time to classify this material at this time. This is why it is only listed as a carcinogen in section 2 and in section 15.

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Alejandro Llanos-Chea et al.
Journal of pediatric gastroenterology and nutrition, 68(4), 509-516 (2018-11-13)
Enteric bacterial pathogens cause diarrheal disease and mortality at significant rates throughout the world, particularly in children younger than 5 years. Our ability to combat bacterial pathogens has been hindered by antibiotic resistance, a lack of effective vaccines, and accurate
Long-term treatment of thalidomide ameliorates amyloid-like pathology through inhibition of ?-secretase in a mouse model of Alzheimer's disease.
He P, et al.
PLoS ONE, 8, e55091-e55091 (2013)
Efficient imaging of amyloid deposits in Drosophila models of human amyloidoses.
Berg I, et al.
Nature Protocols, 5, 935-935 (2010)
Quantifying amyloid beta-peptide (Abeta) aggregation using the Congo red-Abeta (CR-abeta) spectrophotometric assay.
Klunk WE, et al.
Analytical Biochemistry, 266, 66-66 (1999)
Kinetic study and equilibrium isotherm analysis of Congo Red adsorption by clay materials.
Vimonses V, et al.
Chemical Engineering Journal, 148, 354-364 (2009)

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