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Merck
CN

C6146

Sigma-Aldrich

2-巴豆酰辅酶A 锂盐

≥90% (HPLC)

别名:

2-丁烯酰CoA锂盐, 巴豆酰Co A锂盐, 巴豆酰辅酶A 锂盐

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About This Item

经验公式(希尔记法):
C25H40N7O17P3S
分子量:
835.61
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51

质量水平

检测方案

≥90% (HPLC)

形式

powder

储存温度

−20°C

SMILES字符串

[Li].C\C=C\C(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OCC1OC(C(O)C1OP(O)(O)=O)n2cnc3c(N)ncnc23

InChI

1S/C25H40N7O17P3S.Li.H/c1-4-5-16(34)53-9-8-27-15(33)6-7-28-23(37)20(36)25(2,3)11-46-52(43,44)49-51(41,42)45-10-14-19(48-50(38,39)40)18(35)24(47-14)32-13-31-17-21(26)29-12-30-22(17)32;;/h4-5,12-14,18-20,24,35-36H,6-11H2,1-3H3,(H,27,33)(H,28,37)(H,41,42)(H,43,44)(H2,26,29,30)(H2,38,39,40);;/b5-4+;;

InChI key

OXXVXWRNRODUOD-SFKRKKMESA-N

应用

巴豆酰基辅酶A(2-丁烯酰基辅酶A)可用作如恶性疟原虫烯酰基-ACP还原酶和其他烯酰基-CoA还原酶的底物。巴豆酰-CoA可作为底物类似物用于对β-羟酰基-酰基载体蛋白(ACP)脱水酶(FabZ)进行动力学研究。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Weizhi Liu et al.
Biochemical and biophysical research communications, 333(4), 1078-1086 (2005-06-22)
Helicobacter pylori is a gram-negative pathogenic bacterium that causes peptic ulcer disease and gastric cancer, and studies of the related potent enzymes associated with this bacterium are urgent for the discovery of novel drug targets. In bacteria, beta-hydroxyacyl-acyl carrier protein
Mili Kapoor et al.
The Biochemical journal, 381(Pt 3), 725-733 (2004-05-06)
The binding of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum (PfENR) with its substrates and inhibitors has been analysed by SPR (surface plasmon resonance). The binding of the substrate analogue crotonoyl-CoA and coenzyme NADH to PfENR was monitored in real
Neha Kapoor et al.
IUBMB life, 61(11), 1083-1091 (2009-10-28)
A structure-based approach has been adopted to develop 2'-substituted analogs of triclosan. The Cl at position 2' in ring B of triclosan was chemically substituted with other functional groups like NH(2), NO(2) and their inhibitory potencies against PfENR were determined.
Sara Tucci et al.
FEBS letters, 581(8), 1561-1566 (2007-03-27)
An NADH-dependent trans-2-enoyl-CoA reductase (EC1.1.1.36) from the Gram negative spirochete Treponema denticola was identified, expressed and biochemically characterized. The recombinant protein is a monomeric enzyme with a molecular mass of 44 kDa with a specific activity of 43+/-4.8 U/mg (micromol

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