C6013
胆甾醇半琥珀酸酯 三羟甲基氨基甲烷盐
anionic detergent
别名:
3β-Hydroxy-5-cholestene 3-hemisuccinate, CHEMS, CHS, 胆固醇半琥珀酸酯, 胆甾醇琥珀酸酯
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选择尺寸
关于此项目
经验公式（希尔记法）:
C31H50O4 · C4H11NO3
化学文摘社编号:
分子量:
607.86
UNSPSC Code:
12352211
eCl@ss:
39023139
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
胆甾醇半琥珀酸酯 三羟甲基氨基甲烷盐, anionic detergent
SMILES string
NC(CO)(CO)CO.CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)CCC(O)=O
InChI key
SLDYONDUXRBLLR-XTCKSVDZSA-N
InChI
1S/C31H50O4.C4H11NO3/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(35-29(34)14-13-28(32)33)15-17-30(22,4)27(24)16-18-31(25,26)5;5-4(1-6,2-7)3-8/h9,20-21,23-27H,6-8,10-19H2,1-5H3,(H,32,33);6-8H,1-3,5H2/t21-,23+,24+,25-,26+,27+,30+,31-;/m1./s1
biological source
synthetic (organic)
assay
≥98% (TLC)
form
powder
functional group
ester
shipped in
ambient
storage temp.
−20°C
Quality Level
Application
胆固醇半琥珀酸酯三盐用于：
- 制备用于葡聚糖合酶测定的溶解缓冲液
- 制备用于将阿片受体固定在顺磁珠上的免疫沉淀缓冲液。
- 作为脂质体和蛋白突触结合蛋白1的膜稳定剂
- 作为叶酸修饰的自微乳化药物递送系统的组成部分。
- 与正十二烷基 β-D-麦芽糖苷（DDM）一起用于溶解红细胞血影和趋化因子受体CCR1
- 用于溶解蛋白
Biochem/physiol Actions
胆固醇半琥珀酸盐是一种可电离的阴离子洗涤剂，可稳定大的单层囊泡。这些脂质体囊泡作为抗癌药物、寡核苷酸和抗生素的递送剂。据报道胆固醇琥珀酸酯还具有抗增殖活性，并可以在临床上用作抗肿瘤剂。
Preparation Note
浓度为1 mg/ml的半琥珀酸胆固醇三盐在甲醇中生成澄清、无色的溶液。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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P Mazur et al.
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