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Merck
CN

C6003

叶绿酸 钠铜盐

commercial grade, powder

别名:

叶绿素,铜 三钠盐

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关于此项目

经验公式(希尔记法):
C34H31CuN4Na3O6
化学文摘社编号:
分子量:
724.15
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
EC Number:
234-242-5
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产品名称

叶绿酸 钠铜盐,

InChI

1S/C34H36N4O6.Cu.3Na/c1-7-19-15(3)23-12-25-17(5)21(9-10-29(39)40)32(37-25)22(11-30(41)42)33-31(34(43)44)18(6)26(38-33)14-28-20(8-2)16(4)24(36-28)13-27(19)35-23;;;;/h7,12-14,17,21H,1,8-11H2,2-6H3,(H5,35,36,37,38,39,40,41,42,43,44);;;;/q;+2;3*+1/p-5

InChI key

HWDGVJUIHRPKFR-UHFFFAOYSA-I

SMILES string

[Na+].[Na+].[Na+].CCc1c(C)c2cc3c(C=C)c(C)c4cc5nc(C(CCC([O-])=O)C5C)c(CC([O-])=O)c6c(C([O-])=O)c(C)c(cc1n2)n6[Cu]n34

form

powder

technique(s)

microbe id | staining: suitable

color

black, green to very dark green

solubility

H2O: 100 mg/mL, dark green

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

Quality Level

Application

叶绿素铜钠盐已被用于研究叶绿素对辐射诱导的造血综合征的影响。它已被用于研究叶绿素对哺乳期大鼠乳汁中PhIP(2-氨基-1-甲基-6-苯基咪唑[4,5-b]吡啶)及其代谢产物排泄的影响。

Biochem/physiol Actions

叶绿酸是叶绿素的水溶性衍生物。它具有化学预防特性,与许多致突变/致癌分子形成非共价复合物。复合物形成减少了致突变/致癌分子的吸收或允许其排泄。叶绿酸还具有抗氧化,抗细胞凋亡和免疫刺激作用,并具有防止体臭和增加伤口愈合等益处。

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Stephanie Wohllebe et al.
Photochemistry and photobiology, 87(5), 1113-1122 (2011-06-28)
Chlorophyllin kills mosquito larvae (Culex, Aedes) in the aquatic habitat at low concentrations via photodynamic reactions under irradiation. The effects of chlorophyllin were investigated at the cellular level using the transparent larvae of Chaoborus crystallinus as a model system. Their
Sherrill Wesley Josewin et al.
Food microbiology, 76, 219-225 (2018-09-01)
This study evaluated the potential of blue light-emitting diodes (LED) of wavelength 405 and 460 nm in combination with sodium chlorophyllin to inactivate Listeria monocytogenes and Salmonella spp. on cantaloupe rind. A cocktail culture of L. monocytogenes or Salmonella spp. strains
Wei Li et al.
Nanomedicine (London, England), 7(3), 383-392 (2012-03-06)
How to overcome insufficient drug release is an important issue in the drug-delivery system. Here, a novel temperature and UV dual-control poly(N-isopropylacrylamide [PNIPAM]-co-chlorophyllin) nanogel was prepared via the surfactant-free emulsion polymerization. The introduction of hydrophilic chlorophyllin to the PNIPAM chain
Yan-lin Zhang et al.
Zhonghua nei ke za zhi, 51(6), 466-470 (2012-09-05)
To investigate whether chlorophyllin could protect human umbilical vein endothelial cell (HUVEC) against oxidative damage by inducing the expression of heme oxygenase-1 (HO-1) and to explore the underlying mechanism. The cellular protection of chlorophyllin against oxidative damage was detected by
Distribution and metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in female rats and their pups at dietary doses.
Mauthe RJ, et al.
Carcinogenesis, 19, 919-924 (1998)

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