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Merck
CN

C6003

Sigma-Aldrich

叶绿酸 钠铜盐

commercial grade, powder

别名:

叶绿素,铜 三钠盐

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About This Item

经验公式(希尔记法):
C34H31CuN4Na3O6
CAS号:
分子量:
724.15
EC 号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47

product name

叶绿酸 钠铜盐, commercial grade

等级

commercial grade

质量水平

形式

powder

颜色

black
green to very dark green

溶解性

H2O: 100 mg/mL, dark green

应用

diagnostic assay manufacturing
hematology
histology

储存温度

2-8°C

SMILES字符串

[Na+].[Na+].[Na+].CCc1c(C)c2cc3c(C=C)c(C)c4cc5nc(C(CCC([O-])=O)C5C)c(CC([O-])=O)c6c(C([O-])=O)c(C)c(cc1n2)n6[Cu]n34

InChI

1S/C34H36N4O6.Cu.3Na/c1-7-19-15(3)23-12-25-17(5)21(9-10-29(39)40)32(37-25)22(11-30(41)42)33-31(34(43)44)18(6)26(38-33)14-28-20(8-2)16(4)24(36-28)13-27(19)35-23;;;;/h7,12-14,17,21H,1,8-11H2,2-6H3,(H5,35,36,37,38,39,40,41,42,43,44);;;;/q;+2;3*+1/p-5

InChI key

HWDGVJUIHRPKFR-UHFFFAOYSA-I

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应用

叶绿素铜钠盐已被用于研究叶绿素对辐射诱导的造血综合征的影响。它已被用于研究叶绿素对哺乳期大鼠乳汁中PhIP(2-氨基-1-甲基-6-苯基咪唑[4,5-b]吡啶)及其代谢产物排泄的影响。

生化/生理作用

叶绿酸是叶绿素的水溶性衍生物。它具有化学预防特性,与许多致突变/致癌分子形成非共价复合物。复合物形成减少了致突变/致癌分子的吸收或允许其排泄。叶绿酸还具有抗氧化,抗细胞凋亡和免疫刺激作用,并具有防止体臭和增加伤口愈合等益处。

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Daniel T Shaughnessy et al.
PloS one, 6(4), e18707-e18707 (2011-05-05)
Dietary exposures implicated as reducing or causing risk for colorectal cancer may reduce or cause DNA damage in colon tissue; however, no one has assessed this hypothesis directly in humans. Thus, we enrolled 16 healthy volunteers in a 4-week controlled
Amelioration of radiation-induced hematopoietic syndrome by an antioxidant chlorophyllin through increased stem cell activity and modulation of hematopoiesis.
Suryavanshi S, et al.
Free Radical Biology & Medicine, 85, 56-70 (2015)
M Kumar et al.
The British journal of nutrition, 107(7), 1006-1016 (2011-08-06)
The present investigation was carried out to evaluate the hepatoprotective effect of probiotic fermented milk (FM) containing Lactobacillus rhamnosus GG and Lactobacillus casei strain Shirota, alone as well as in combination with chlorophyllin (CHL) as an antioxidant agent in male
Jingqun Gao et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 849-857 (2011-06-18)
In this paper, the chlorophyll derivatives, metallochlorophyllin (Chl-M) (M=Fe, Zn and Cu) including chlorophyllin iron (Chl-Fe), chlorophyllin zinc (Chl-Zn) and chlorophyllin copper (Chl-Cu), were adopted as sonosensitizers to combine with ultrasonic irradiation, and the sonodynamic damage of bovine serum albumin
Maria Rosaria Grossi et al.
Toxicology letters, 214(3), 235-242 (2012-09-19)
Chlorophyllin (CHL), a water soluble derivative of chlorophyll has been shown to have both anticarcinogenic and antigenotoxic properties. We evaluated the protective effects of CHL (25μM in vitro, 4 and 100mg/kg. b.w.) on the clastogenic action of two model carcinogens

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