推荐产品
产品名称
(-)-可替宁, ≥98%
质量水平
方案
≥98%
表单
crystals
沸点
250 °C/150 mmHg (lit.)
mp
40-42 °C (lit.)
储存温度
2-8°C
SMILES字符串
CN1[C@@H](CCC1=O)c2cccnc2
InChI
1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1
InChI key
UIKROCXWUNQSPJ-VIFPVBQESA-N
基因信息
human ... CYP1A2(1544) , CYP2A6(1548)
mouse ... Cyp2a5(13087)
正在寻找类似产品? 访问 产品对比指南
一般描述
Cotinine is an alkaloid extracted from tobacco leaves. It can cross the blood-brain barrier. Cotinine is used to treat Alzheimer′s disease (AD), schizophrenia and post-traumatic stress disorder (PTSD).
应用
Cotinine has been used:
- for oxygen-glucose deprivation (OGD) studies to model ischemic stroke
- as a standard to determine serum cotinine measurements using liquid chromatography with tandem mass spectrometry (LC-MS/MS)
- to evaluate the adverse developmental potential of cotinine
- to assess cognitive behavior in mice
生化/生理作用
尼古丁在人体内的主要代谢物。
警示用语:
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
230.0 °F - closed cup
闪点(°C)
110 °C - closed cup
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
监管及禁止进口产品
从最新的版本中选择一种:
分析证书(COA)
Nicotine and electronic cigarette (E-Cig) exposure decreases brain glucose utilization in ischemic stroke
Journal of Neurochemistry, 147(2), 204-221 (2018)
Evaluation of serum cotinine cut-off to distinguish smokers from nonsmokers in the Korean population
Annals of Laboratory Medicine, 36(5), 427-433 (2016)
Cotinine administration improves impaired cognition in the mouse model of Fragile X syndrome
The European Journal of Neuroscience, 45(4), 490-498 (2017)
Long-term cardiovascular reprogramming by short-term perinatal exposure to nicotine's main metabolite cotinine
Acta Paediatrica (Oslo, Norway : 1992), 107(4), 638-646 (2018)
Cotinine: beyond that expected, more than a biomarker of tobacco consumption
Frontiers in Pharmacology, 3, 173-173 (2012)
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门