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Merck
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主要文件

C5762

Sigma-Aldrich

多聚乙酸 钠盐 来源于大肠杆菌

别名:

聚[2,8-(N-乙酰神经氨酸钠盐)]

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About This Item

线性分子式:
(C11H16NNaO8)n
CAS号:
MDL编号:
UNSPSC代码:
51102829
NACRES:
NA.76

表单

powder

质量水平

溶解性

H2O: 50 mg/mL

抗生素抗菌谱

viruses

作用机制

enzyme | inhibits

储存温度

−20°C

InChI

1S/C11H20NO7.3Na/c1-6(15)12-10-7(16)4-9(18-3-2-13)19-11(10)8(17)5-14;;;/h3,7-11,13-14,16-17H,2,4-5H2,1H3,(H,12,15);;;/q;3*+1

InChI key

IPYNPWIUCZLARC-UHFFFAOYSA-N

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应用

多聚乙酸用于研究蛋白质聚唾液酸化过程。它是 CMP-NeuAc:(NeuAcα2→8)n (聚唾液酸)唾液酸转移酶的底物。

其他说明

保持容器密闭,置于干燥通风处。保持干燥

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J Roth et al.
Proceedings of the National Academy of Sciences of the United States of America, 85(9), 2999-3003 (1988-05-01)
A unique structural feature of the neural cell adhesion molecule N-CAM is the presence of homopolymers of alpha (2----8)-linked sialic acid units. We have used two specific probes for the detection of poly(sialic acid) in normal human kidney and Wilms
J Finne et al.
Journal of immunology (Baltimore, Md. : 1950), 138(12), 4402-4407 (1987-06-15)
The structurally similar polysialic acid capsules of group B meningococci and Escherichia coli K1 are poor immunogens, and attempts are currently being made to improve their immunogenicity by chemical modifications. An IgG monoclonal antibody to these polysialic acid capsules was
J Roth et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(7), 1969-1973 (1987-04-01)
We report the presence of alpha(2----8)-linked polysialic acid as detected with a monoclonal antibody outside the nervous tissue in the postnatal developing rat kidney. By immunoblot analysis, the reactivity was confined to a broad band of apparent molecular mass 200-250
Nina Westphal et al.
Scientific reports, 7(1), 13631-13631 (2017-10-21)
The neural cell adhesion molecule (NCAM) is the major carrier of polysialic acid (PSA) which modulates NCAM functions of neural cells at the cell surface. In previous studies, we have shown that stimulation of cultured neurons with surrogate NCAM ligands

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