C5743
Cilastatin sodium salt
powder, ≥98% (HPLC)
别名:
Cilastatin sodium
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C16H25N2NaO5S
化学文摘社编号:
分子量:
380.43
MDL number:
UNSPSC Code:
12352204
EC Number:
279-694-4
NACRES:
NA.77
产品名称
Cilastatin sodium salt, ≥98% (HPLC)
SMILES string
[Na+].S(C[C@H](N)C(=O)[O-])CCCC\C=C(/NC(=O)[C@@H]1C(C1)(C)C)\C(=O)O
InChI key
QXPBTTUOVWMPJN-QBNHLFMHSA-M
InChI
1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11+;/m1./s1
biological source
synthetic (organic)
assay
≥98% (HPLC)
form
powder
solubility
water: 10 mg/mL, clear, colorless to faintly yellow
storage temp.
2-8°C
Quality Level
正在寻找类似产品? 访问 产品对比指南
Biochem/physiol Actions
Inhibitor of dehydropeptidase I
Inhibitor of the renal enzyme dehydropeptidase I and some bacterial zinc-containing β-lactamases. By these action, cilastatin suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy.
General description
Cilastatin sodium salt is off-white to yellowish-white, hygroscopic, amorphous compound. It is derivatized from heptenoic acid. Its molecular mass is 380.43 g.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
First-order derivative ultraviolet spectrophotometry of imipenem-cilastatin formulations.
Tabbouche OS and Soukkariyyeh I
Journal of Taibah University Medical Sciences, 9(3), 178-181 (2014)
Jinkyung Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 119(9) (2022-02-25)
Aminoglycosides (AGs) are commonly used antibiotics that cause deafness through the irreversible loss of cochlear sensory hair cells (HCs). How AGs enter the cochlea and then target HCs remains unresolved. Here, we performed time-lapse multicellular imaging of cochlea in live
Saurav Roy Choudhury et al.
Cell, 178(5), 1205-1221 (2019-08-24)
A hallmark feature of inflammation is the orchestrated recruitment of neutrophils from the bloodstream into inflamed tissue. Although selectins and integrins mediate recruitment in many tissues, they have a minimal role in the lungs and liver. Exploiting an unbiased in vivo
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持