所有图片(1)
About This Item
经验公式（希尔记法）:
C14H22O4
CAS号:
分子量:
254.32
MDL编号:
UNSPSC代码:
41121801
PubChem化学物质编号:
NACRES:
NA.77
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质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 5 mg/mL, clear
储存温度
2-8°C
SMILES字符串
CCCCCCCCC1OC(=O)C(=C)C1C(O)=O
InChI
1S/C14H22O4/c1-3-4-5-6-7-8-9-11-12(13(15)16)10(2)14(17)18-11/h11-12H,2-9H2,1H3,(H,15,16)
InChI key
VCWLZDVWHQVAJU-UHFFFAOYSA-N
应用
C75用于：
- 作为脂肪酸合酶（FASN）抑制剂，测试其相较于二甲双胍，对FASN的直接抑制作用以及减弱乳腺球形成的能力
- 作为抑制神经胶质瘤干细胞（GSC）中脂肪酸合成的药理抑制剂
- 作为FAS 抑制剂 对Chang细胞进行预处理，以抑制脂肪生成并逆转过氧化氢诱导的衰老
生化/生理作用
C75有助于提高电离辐射的抗癌能力。
C75是一种新型、有效的脂肪酸合成酶（FAS）合成抑制剂，可用作研究代谢紊乱和癌症中脂肪酸合成的工具。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Differential in radiosensitizing potency of enantiomers of the fatty acid synthase inhibitor C75
Rae C, et al.
Chirality, 29(1), 10-13 (2017)
Song-Hyo Jin et al.
PLoS neglected tropical diseases, 11(6), e0005687-e0005687 (2017-06-22)
Leprosy is a chronic infectious disease that is caused by the obligate intracellular pathogen Mycobacterium leprae (M.leprae), which is the leading cause of all non-traumatic peripheral neuropathies worldwide. Although both myelinating and non-myelinating Schwann cells are infected by M.leprae in
Cheulhee Jung et al.
Analytical and bioanalytical chemistry, 408(30), 8583-8591 (2016-04-02)
There are various ways that priming can occur in nucleic acid amplification reactions. While most reactions rely on a primer to initiate amplification, a mechanism for DNA amplification has been developed in which hairpin sequences at the 3' terminus of
Satoshi Kimura et al.
Nucleic acids research, 45(22), 12974-12986 (2017-10-27)
Post-transcriptional modifications of ribosomal RNAs (rRNAs) are involved in ribosome biogenesis and fine-tuning of translation. 5-Hydroxycytidine (ho5C), a modification of unknown biogenesis and function, is present at position 2501 of Escherichia coli 23S rRNA. We conducted a genome-wide screen in
Marcelo M Samsa et al.
PLoS pathogens, 5(10), e1000632-e1000632 (2009-10-24)
Dengue virus is responsible for the highest rates of disease and mortality among the members of the Flavivirus genus. Dengue epidemics are still occurring around the world, indicating an urgent need of prophylactic vaccines and antivirals. In recent years, a
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