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质量水平
检测方案
≥99% (TLC)
形式
crystalline
颜色
white
溶解性
H2O: 1.7 g/mL (stable for several days at 4°C.)
ethanol: 80 mg/mL (stable for several days at 4°C.)
储存温度
2-8°C
SMILES字符串
Cl.CC(C[N](C)(C)C)OC(N)=O
InChI
1S/C7H17N2O2.ClH/c1-6(11-7(8)10)5-9(2,3)4;/h6H,5H2,1-4H3,(H2,8,10);1H
InChI key
AIRHOJQHGLTTTB-UHFFFAOYSA-N
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应用
Carbamyl-β-methylcholine chloride has been used in western blotting and bactericidal assay. It has also been used in concentration-response studies with isolated atrial preparation.
生化/生理作用
Carbamyl-β-methylcholine has a selective action on urinary bladder and intestine. It induces smooth muscle tension in the bladder. Its main function is to induce detrusor muscle action, mediated by postganglionic parasympathetic effector cells. Nausea, flushing, sweating, abdominal cramps are some of the side effect caused by carbamyl-β-methylcholine.
注意
Hygroscopic.
底物
Muscarinic acetylcholine receptor agonist that is not a substrate for acetylcholinesterase.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Pharmacology for the Primary Care Provider, 380-380 (2008)
Remodeling of cardiac cholinergic innervation and control of heart rate in mice with streptozotocin-induced diabetes
Mabe AM and Hoover DB
Autonomic Neuroscience : Basic & Clinical, 162(1-2), 24-31 (2011)
Adult and Pediatric Urology, 1, 1127-1127 (2002)
Ana Beatriz Albino de Almeida et al.
Journal of medicinal food, 15(4), 378-383 (2011-12-24)
Arctium lappa L. has been used in folk medicine as a diuretic, depurative, and digestive stimulant and in dermatological conditions. The mechanisms involved in the anti-ulcerogenic activity of the sesquiterpene onopordopicrin (ONP)-enriched fraction (termed the ONP fraction), obtained from A.
Jagmohan Singh et al.
Gastroenterology, 143(5), 1308-1318 (2012-08-07)
Patients with systemic sclerosis (SSc) have impairments in gastrointestinal smooth muscle function. The disorder has been associated with circulating antibodies to cholinergic muscarinic the type-3 receptor (M(3)-R). We investigated whether it is possible to neutralize these antibodies with pooled human
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