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Merck
CN

C5243

Monoclonal Anti-Cystatin B 小鼠抗

~2 mg/mL, clone RJMW-2E7, purified immunoglobulin, buffered aqueous solution

别名:

CSTB, EPM1, PME, STEFIN B, STFB

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UNSPSC Code:
12352203
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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

RJMW-2E7, monoclonal

form

buffered aqueous solution

mol wt

antigen ~12 kDa

species reactivity

human, monkey

concentration

~2 mg/mL

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, western blot: 1-2 μg/mL using extracts of MCF7 cells (is recommended using extracts of MCF7 cells.)

isotype

IgG1

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CSTB(1476)

Immunogen

human cystatin B purified from human muscle and spleen.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Physical form

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Kirsi Alakurtti et al.
European journal of human genetics : EJHG, 13(2), 208-215 (2004-10-16)
Loss-of-function mutations in the cystatin B (CSTB), a cysteine protease inhibitor, gene underlie progressive myoclonus epilepsy of Unverricht-Lundborg type (EPM1), characterized by myoclonic and tonic-clonic seizures, ataxia and a progressive course. A minisatellite repeat expansion in the promoter region of
Chan Chung et al.
Human molecular genetics, 25(7), 1434-1446 (2016-02-26)
Niemann-Pick C1 (NPC) disease, an autosomal recessive lipid trafficking disorder caused by loss-of-function mutations in the NPC1 gene, is characterized by progressive neurodegeneration resulting in cognitive impairment, ataxia and early death. Little is known about the cellular pathways leading to
A Azimi et al.
British journal of cancer, 110(10), 2489-2495 (2014-04-12)
Disseminated cutaneous malignant melanoma (CMM) is commonly unresponsive to standard chemotherapies, and there are as yet no predictive markers of therapy response. In the present study we collected fresh-frozen pretreatment lymph-node metastasis samples (n=14) from melanoma patients with differential response

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