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Merck
CN

C5132

咔唑

≥95% purity (GC), powder

别名:

二苯并吡咯; 二苯基吡咯

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关于此项目

经验公式(希尔记法):
C12H9N
化学文摘社编号:
分子量:
167.21
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
201-696-0
MDL number:
Beilstein/REAXYS Number:
3956
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产品名称

咔唑, ≥95% (GC)

InChI

1S/C12H9N/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11/h1-8,13H

InChI key

UJOBWOGCFQCDNV-UHFFFAOYSA-N

SMILES string

c1ccc2c(c1)[nH]c3ccccc23

vapor pressure

400 mmHg ( 323 °C)

assay

≥95% (GC)

form

powder

technique(s)

titration: suitable

color

white to tan

bp

355 °C (lit.)

mp

243-246 °C (lit.)

solubility

acetone: 50 mg/mL

density

1.1 g/cm3 at 18 °C

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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General description

咔唑是一种芳香族杂环有机分子。

Application

咔唑已用于糖醛酸的测定。

Biochem/physiol Actions

咔唑主要与 DNA 相互作用并对其造成损伤。这些事件可抑制新 DNA 或 RNA 的合成。咔唑衍生物具有抗微生物、抗肿瘤、抗癫痫、抗组胺、抗氧化、抗炎、抗腹泻、镇痛、神经保护和胰脂肪酶抑制活性。

Analysis Note

其可能含有黑色颗粒物。

pictograms

Health hazard

signalword

Warning

Hazard Classifications

Aquatic Chronic 4 - Carc. 2 - Muta. 2

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

428.0 °F - closed cup

flash_point_c

220.0 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A complete set of hyaluronan fragments obtained from hydrolysis catalyzed by hyaluronidase: Application to studies of hyaluronan mass distribution by simple HPLC devices.
Tranchepain F, et al.
Analytical Biochemistry, 348, 232-242 (2006)
CARBAZOLE DERIVATIVES IN CANCER TREATMENT-A REVIEW.
Kanneti Naga M, et al.
World Journal of Pharmacy and Pharmaceutical Sciences (2015)
Shen H Tan et al.
Organic letters, 14(22), 5621-5623 (2012-10-31)
The racemic modification of the Aspidosperma alkaloid limaspermidine (1) has been prepared in ten steps including one involving a Raney-cobalt-mediated tandem reductive cyclization of nitrile 8 to give the tetracyclic system 9b. Compound (±)-1 has been converted over two steps
Jong-Kwan Bin et al.
Advanced materials (Deerfield Beach, Fla.), 24(21), 2911-2915 (2012-05-03)
A new carbazole derivative with two carbazole moieties on the C3 and C6 positions of carbazole and triphenylsilane directly linked to the N of carbazole is successfully used as a highly efficient blue phosphorescent host in an organic light-emitting diode
Shinya Oishi et al.
Journal of medicinal chemistry, 53(13), 5054-5058 (2010-06-05)
Mitotic kinesin spindle protein (KSP) is involved in the assembly of the bipolar spindle during cell division. On the basis of a common 2,3-fused indole substructure within the complex frameworks of terpendole E and other KSP inhibitors, the carbazoles with

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