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Merck
CN

C5020

Sigma-Aldrich

头孢唑啉 钠盐

89.1-110.1%

别名:

Cefazoline sodium, Monosodium cefazolin

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About This Item

经验公式(希尔记法):
C14H13N8NaO4S3
CAS号:
分子量:
476.49
Beilstein:
3585038
EC 号:
MDL编号:
UNSPSC代码:
51282532
PubChem化学物质编号:
NACRES:
NA.76

质量水平

方案

89.1-110.1%

表单

powder

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

作用机制

cell wall synthesis | interferes

储存温度

2-8°C

SMILES字符串

[Na+].Cc1nnc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn4cnnn4)C3=O)C([O-])=O)s1

InChI

1S/C14H14N8O4S3.Na/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21;/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26);/q;+1/p-1/t9-,12-;/m1./s1

InChI key

FLKYBGKDCCEQQM-WYUVZMMLSA-M

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一般描述

Chemical structure: ß-lactam

生化/生理作用

Used to study the effect of expression, binding and inhibition of penicillin-binding proteins, especially PBP2 and PBP4 on bacterial cell wall mucopeptide synthesis.

制备说明

Freely soluble in water, very slightly soluble in chloroform and ethanol.

其他说明

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

象形图

Health hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

监管及禁止进口产品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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Bo-Bae Seo et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 106(2), 751-759 (2017-03-24)
An injectable hydrogel system with sustained bone morphogenetic protein 2 (BMP-2) release ability was developed for vertical bone regeneration at peri-implant sites and enhanced osseointegration of dental implants. In three young male beagle dogs, a pair of defects was created
Mei Zhang et al.
Therapeutic drug monitoring, 40(6), 682-692 (2018-07-18)
Pharmacokinetic studies and therapeutic drug monitoring of antibiotics require a simple, rapid, and reliable analytical method for monitoring the concentrations in plasma, including unbound concentrations for highly protein-bound drugs. The aim of the current work was to develop and validate
Francesca D'Este et al.
Journal of peptide science : an official publication of the European Peptide Society, 23(10), 777-789 (2017-07-15)
The prevention of implant-associated infection, one the most feared complications in orthopaedic surgery, remains a major clinical challenge and urges development of effective methods to prevent bacterial colonization of implanted devices. Alpha-helical antimicrobial peptides (AMPs) may be promising candidates in
Tim Garrett et al.
Emergency medicine Australasia : EMA, 24(4), 383-392 (2012-08-07)
Cellulitis is a common presentation to the ED and a significant cause of hospitalization that can be managed in hospital-in-the-home programmes. Current clinical-practice guidelines recommend once or twice-daily i.v. antibiotics; however, there is an absence of data describing the impact
Colleen K Cagno et al.
American family physician, 86(1), 59-65 (2012-09-12)
Group B streptococcus is the leading cause of early-onset neonatal sepsis in the United States. Universal screening is recommended for pregnant women at 35 to 37 weeks' gestation. The Centers for Disease Control and Prevention recently updated its guideline for

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