跳转至内容
Merck
CN
所有图片(1)

主要文件

查看所有文档

安全信息

C4991

Sigma-Aldrich

头孢甘氨酸

≥97% (HPLC), solid

别名:

NSC 318735

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C45H53NO14
CAS号:
71610-00-9
分子量:
831.90
MDL编号:
MFCD01075131
UNSPSC代码:
12352200
PubChem化学物质编号:
24724441
NACRES:
NA.77

质量水平

100

方案

≥97% (HPLC)

表单

solid

溶解性

DMSO: soluble 14 mg/mL

抗生素抗菌谱

neoplastics

作用机制

DNA synthesis | interferes

储存温度

room temp

SMILES字符串

C\C=C(/C)C(=O)N[C@H]([C@@H](O)C(=O)O[C@H]1C[C@@]2(O)[C@@H](OC(=O)c3ccccc3)C4[C@@](C)([C@@H](O)C[C@H]5OC[C@@]45OC(C)=O)C(=O)[C@H](OC(C)=O)C(=C1C)C2(C)C)c6ccccc6

InChI

1S/C45H53NO14/c1-9-23(2)39(52)46-33(27-16-12-10-13-17-27)34(50)41(54)58-29-21-45(55)38(59-40(53)28-18-14-11-15-19-28)36-43(8,30(49)20-31-44(36,22-56-31)60-26(5)48)37(51)35(57-25(4)47)32(24(29)3)42(45,6)7/h9-19,29-31,33-36,38,49-50,55H,20-22H2,1-8H3,(H,46,52)/b23-9+/t29-,30-,31+,33-,34+,35+,36?,38-,43+,44-,45+/m0/s1

InChI key

DBXFAPJCZABTDR-UJLUYDJNSA-N

正在寻找类似产品? 访问 产品对比指南

一般描述

化学结构:β-内酰胺

应用

头孢甘氨酸已被用于鉴定液体培养物中的真菌紫杉醇（抗癌药）。

生化/生理作用

头孢甘氨酸是从红豆杉中分离得到的，可用作抗真菌剂。
三尖杉宁碱是一种具有抗肿瘤、抗增殖特性的紫杉醇衍生物。

象形图

CorrosionExclamation mark
GHS05,GHS07

警示用语：

Danger

危险声明

H315,H318,H335

危险分类

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
0000403335
0000403335
0000133141
0000057412
0000019495

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Jiang-Wei Zhang et al.
Drug metabolism and disposition: the biological fate of chemicals, 36(2), 418-426 (2007-11-28)
To investigate how taxane's substituents at C3' affect its metabolism, we compared the metabolism of cephalomannine and paclitaxel, a pair of analogs that differ slightly at the C3' position. After cephalomannine was incubated with human liver microsomes in an NADPH-generating
Kannan Vivekanandan et al.
Rapid communications in mass spectrometry : RCM, 20(11), 1731-1735 (2006-05-06)
A strategy is developed for the identification of isocephalomannine in the presence of alkali metal ion adducts and other cephalomannine isomers in a paclitaxel active pharmaceutical ingredient. Intact molecular ion analyses and a sub-structural study have been performed for the
K C Chan et al.
Journal of chromatography. B, Biomedical applications, 657(2), 301-306 (1994-07-15)
High-performance liquid chromatography (HPLC) and micellar electrokinetic chromatography (MEKC) were applied for the separation of taxol, cephalomannine, and baccatin III in crude extracts from the needle and bark of Taxus species. The chromatogram of the bark extract was cleaner than
G Moyna et al.
Journal of chemical information and computer sciences, 36(6), 1224-1227 (1996-11-01)
A simple iterative method for superimposing sets of NMR derived structures and calculation of the root mean square deviation (RMSD) of the sets is described. It was compared to the commonly used algorithm involving pairwise best fitting in the conformational
Hongbo Wang et al.
Cancer letters, 268(1), 89-97 (2008-05-17)
Lx2-32c, a novel taxane derivative, is a semisynthetic analogue from cephalomannine. Its antitumor activity in vivo and in vitro was investigated in this study. Lx2-32c was cytotoxic (IC50=1.7+/-1.6nM) to various human tumor cell lines after 72h incubation. In vitro it
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门