推荐产品
产品名称
I 型胶原蛋白 −FITC 共轭物 来源于牛皮, ~1 mg/mL, solution
生物来源
bovine skin
质量水平
表单
solution
浓度
~1 mg/mL
运输
wet ice
储存温度
−20°C
基因信息
cow ... COL1A1(282187) , COL1A2(282188)
human ... MMP1 (includes EG:4312)
mouse ... MMP1 (includes EG:4312)
rat ... MMP1 (includes EG:4312)
一般描述
I型胶原蛋白是肌腱和骨骼的主要胶原蛋白，但广泛分布于其他组织，例如皮肤、角膜、牙本质、心脏瓣膜、肺、肝、筋膜和疤痕组织。
应用
来自牛皮肤的I型胶原蛋白FITC共轭物已被用于I型胶原蛋白凝胶变形分析。它也已被用于涂覆硅弹性膜，以用于多种实验研究的细胞接种。它也可用作检测细胞培养物中哺乳动物胶原酶活性的底物。
生化/生理作用
胶原蛋白I提供了机械稳定性，为多种器官，筋，韧带，皮肤，角膜，骨骼和牙本质提供了力量和坚固性。
外形
以 0.01M 乙酸形式提供。
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Faceshields, Gloves, Goggles
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Rachel M Brunetti et al.
The Journal of cell biology, 221(2) (2021-12-30)
To control their movement, cells need to coordinate actin assembly with the geometric features of their substrate. Here, we uncover a role for the actin regulator WASP in the 3D migration of neutrophils. We show that WASP responds to substrate
ROCK-and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo
Wyckoff JB, et al.
Current Biology, 16(15), 1515-1523 (2006)
Collagen: structure and mechanics, an introduction
Collagen, 1-13 (2008)
Processing of collagen-based biomaterials and the resulting materials properties
Meyer M, et al.
BioMedical Engineering OnLine, 18 (2019)
Sjors Maassen et al.
Free radical biology & medicine, 188, 287-297 (2022-06-27)
5-methoxy tryptophan (5-MTP) is an anti-fibrotic metabolite made by fibroblasts and epithelial cells, present in a micromolar concentrations in human blood, and is associated with the progression of fibrotic kidney disease, but the mechanism is unclear. Here, we show by
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