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主要文件

C4361

Bovine Collagen Type I

Name: Bovine Collagen Type I
Brand: SIGMA

from bovine skin, liquid, 1 mg/mL, FITC Conjugated, used for gel analysis, cell seeding, and collagenase assays

别名:

Collagen from bovine skin

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About This Item

CAS号:

308064-12-2

MDL编号:

MFCD02264428

UNSPSC代码:

12352202

NACRES:

NA.32

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1 of 4

此商品	779202	CRM47949	CRM44609
387614 环氧乙烷	779202 环氧乙烷溶液	CRM47949 环氧乙烷标准液 CRM	CRM44609 环氧乙烷溶液
assay ≥99.5%	assay -	assay -	assay -
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 100
storage temp. 2-8°C	storage temp. -	storage temp. 2-8°C	storage temp. 2-8°C
bp 10.7 °C (lit.)	bp -	bp -	bp -
refractive index n20/D 1.3597 (lit.)	refractive index -	refractive index -	refractive index -
density 0.882 g/mL at 25 °C (lit.)	density -	density -	density -

一般描述

I型胶原蛋白是肌腱和骨骼的主要胶原蛋白，但广泛分布于其他组织，例如皮肤、角膜、牙本质、心脏瓣膜、肺、肝、筋膜和疤痕组织。[1]

应用

来自牛皮肤的I型胶原蛋白FITC共轭物已被用于I型胶原蛋白凝胶变形分析。[2]它也已被用于涂覆硅弹性膜，以用于多种实验研究的细胞接种。[3]它也可用作检测细胞培养物中哺乳动物胶原酶活性的底物。

生化/生理作用

胶原蛋白I提供了机械稳定性，为多种器官，筋，韧带，皮肤，角膜，骨骼和牙本质提供了力量和坚固性。[4]

外形

以 0.01M 乙酸形式提供。

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Faceshields, Gloves, Goggles

技术规格说明书

历史批次信息供参考:

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Live free or die: Stretch-induced apoptosis occurs when adaptive reorientation of annulus fibrosus cells is restricted

Abbott RD, et al.

Biochemical and Biophysical Research Communications, 421(2), 361-366 (2012)

Modified polyelectrolyte complex fibrous scaffold as a matrix for 3D cell culture.

Benjamin C U Tai et al.

Biomaterials, 31(23), 5927-5935 (2010-05-18)

The paradigm of scaffold tissue engineering relies on the provision of an appropriate environment for cell growth, which includes both structural support and the presentation of cellular signals. In terms of biosignal presentation, fibrous scaffolds by interfacial polyelectrolyte complexation (IPC)

Mitochondrial interaction of fibrosis-protective 5-methoxy tryptophan enhances collagen uptake by macrophages.

Sjors Maassen et al.

Free radical biology & medicine, 188, 287-297 (2022-06-27)

5-methoxy tryptophan (5-MTP) is an anti-fibrotic metabolite made by fibroblasts and epithelial cells, present in a micromolar concentrations in human blood, and is associated with the progression of fibrotic kidney disease, but the mechanism is unclear. Here, we show by

Evidence for altered synthesis of type II collagen in patients with osteoarthritis.

F Nelson et al.

The Journal of clinical investigation, 102(12), 2115-2125 (1998-12-17)

There is evidence to suggest that the synthesis of type II collagen is increased in osteoarthritis (OA). Using an immunoassay, we show that the content of the C-propeptide of type II procollagen (CPII), released extracellularly from the newly synthesized molecule

MicroRNA miR-24-3p Mediates the Negative Regulation of Lipopolysaccharide-Induced Endometrial Inflammatory Response by Targeting TNF Receptor-Associated Factor 6 (TRAF6).

Ayodele Olaolu Oladejo et al.

Journal of inflammation research, 15, 807-825 (2022-02-18)

Endometritis is a female reproductive disease that affects the cattle industries development and microRNAs (miRNAs) play a pivotal role and critical regulators of the innate immune response in varieties of diseases. The present study intends to investigate the regulatory role

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主要文件

Bovine Collagen Type I

from bovine skin, liquid, 1 mg/mL, FITC Conjugated, used for gel analysis, cell seeding, and collagenase assays

About This Item

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