C4284
β-Chloro-D-alanine hydrochloride
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关于此项目
线性分子式:
C3H6NO2Cl · HCl
化学文摘社编号:
分子量:
160.00
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
InChI key
IENJPSDBNBGIEL-HSHFZTNMSA-N
SMILES string
Cl.N[C@H](CCl)C(O)=O
InChI
1S/C3H6ClNO2.ClH/c4-1-2(5)3(6)7;/h2H,1,5H2,(H,6,7);1H/t2-;/m1./s1
assay
≥98% (TLC)
form
powder
solubility
water: 50 mg/mL, clear to very slightly hazy, colorless
storage temp.
−20°C
Quality Level
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
J M Manning et al.
Proceedings of the National Academy of Sciences of the United States of America, 71(2), 417-421 (1974-02-01)
The D- and L-isomers of beta-chloroalanine inhibit the growth of Diplococcus pneumoniae, Streptococcus pyogenes, Bacillus subtilis, and Escherichia coli. With pneumococcus the inhibition by beta-chloro-D-alanine is completely prevented by either D-alanine or D-alanyl-D-alanine, while L-alanine is not effective in preventing
Yuki Ogasawara et al.
Journal of biochemical and biophysical methods, 51(2), 139-150 (2002-06-14)
A highly sensitive method has been developed for the determination of gamma-cystathionase (EC. 4.4.1.1.) activity in rat tissues using beta-chloro-L-alanine as a substrate. This method is based on colorimetry for the determination of pyruvate produced from beta-chloro-L-alanine with the beta-elimination
Agnieszka Robaszkiewicz et al.
Mechanisms of ageing and development, 129(10), 572-579 (2008-07-01)
The increase in the amount of oxidatively modified proteins is a hallmark of ageing and age-related disorders. This paper is aimed at a verification of the hypothesis that N-chloroamino acids, products of reaction between hypochlorite generated in vivo under pathological
Jorge Cerbón et al.
The Biochemical journal, 388(Pt 1), 169-176 (2004-11-25)
We recently reported that DAG (diacylglycerol) generated during sphingomyelin synthesis plays an important role in protein kinase C activation and cell proliferation in Madin-Darby canine kidney cells [Cerbon and Lopez-Sanchez (2003) Biochem. J. 373, 917-924]. In yeast cells, IPC (inositol
Brooke S Wright et al.
Archives of biochemistry and biophysics, 415(2), 184-192 (2003-07-02)
Sphinganine and 4-hydroxysphinganine (phytosphingosine) are the predominant free long-chain bases in lipid extracts of plant tissues. While the synthesis of sphinganine in plants has been investigated, the metabolic origin of 4-hydroxysphinganine is not known. Three different approaches utilizing fumonisin B(1)
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