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蒸汽压
0.01 mmHg ( 47 °C)
质量水平
方案
≥99% (HPLC)
表单
powder
沸点
298 °C (lit.)
mp
68-73 °C (lit.)
SMILES字符串
O=C1Oc2ccccc2C=C1
InChI
1S/C9H6O2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H
InChI key
ZYGHJZDHTFUPRJ-UHFFFAOYSA-N
基因信息
rat ... Maoa(29253) , Maob(25750)
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应用
香豆素可用作制备或合成基于香豆素的抗凝血剂、抗炎剂和抗氧化剂超氧化物清除剂的前体分子。
警示用语:
Danger
危险声明
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Skin Sens. 1
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 1
闪点(°F)
323.6 °F - closed cup
闪点(°C)
162 °C - closed cup
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
从最新的版本中选择一种:
分析证书(COA)
Medicinal research reviews, 23(3), 322-345 (2003-03-21)
Numerous plant-derived compounds have been evaluated for inhibitory effects against HIV replication, and some coumarins have been found to inhibit different stages in the HIV replication cycle. This review article describes recent progress in the discovery, structure modification, and structure-activity
Molecular nutrition & food research, 54(2), 228-239 (2009-12-22)
Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties. For the carcinogenic effect, a genotoxic mechanism was considered possible, but was discounted by the European Food Safety Authority in 2004 based on new evidence. This allowed the derivation of
Chemical communications (Cambridge, England), 49(18), 1811-1813 (2013-01-26)
A photo-switchable fluorescent flagging approach has been developed to identify photoaffinity-labeled peptides in target protein. Upon photochemical release of the ligand, the protein was newly modified with a coumarin in place of the previously attached biotin. It allowed us to
The journal of physical chemistry. A, 117(7), 1474-1482 (2013-01-25)
A coumarin-amide-dipicolylamine linkage (L) was synthesized and used as a fluorescent receptor for metal cations in water. The receptor dissolved in water with neutral pH shows almost no fluorescence due to the photoinduced electron transfer (PET) from the amide and
Bioorganic & medicinal chemistry, 17(18), 6547-6559 (2009-09-01)
The presumption that some coumarins might be lead compounds in the search for new differentiation agents against leukemia is based on the fact that natural coumarins, 5-(3-methyl-2-butenyloxy)-6,7-methylenedioxycoumarin (C-2) and 5-methoxy-6,7-methylenedioxycoumarin (C-1) inhibit proliferation and induce differentiation in U-937 cells [Riveiro
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