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Merck
CN

C4261

Sigma-Aldrich

香豆素

≥99% (HPLC)

别名:

1,2-苯并吡喃酮, 1-苯并吡喃-2-酮, 2H-苯并吡喃-2-酮

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About This Item

经验公式(希尔记法):
C9H6O2
CAS号:
分子量:
146.14
Beilstein:
383644
EC 号:
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.25

蒸汽压

0.01 mmHg ( 47 °C)

质量水平

方案

≥99% (HPLC)

表单

powder

沸点

298 °C (lit.)

mp

68-73 °C (lit.)

SMILES字符串

O=C1Oc2ccccc2C=C1

InChI

1S/C9H6O2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H

InChI key

ZYGHJZDHTFUPRJ-UHFFFAOYSA-N

基因信息

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应用

香豆素可用作制备或合成基于香豆素的抗凝血剂、抗炎剂和抗氧化剂超氧化物清除剂的前体分子。

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Skin Sens. 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

闪点(°F)

323.6 °F - closed cup

闪点(°C)

162 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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分析证书(COA)

Lot/Batch Number

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Donglei Yu et al.
Medicinal research reviews, 23(3), 322-345 (2003-03-21)
Numerous plant-derived compounds have been evaluated for inhibitory effects against HIV replication, and some coumarins have been found to inhibit different stages in the HIV replication cycle. This review article describes recent progress in the discovery, structure modification, and structure-activity
Klaus Abraham et al.
Molecular nutrition & food research, 54(2), 228-239 (2009-12-22)
Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties. For the carcinogenic effect, a genotoxic mechanism was considered possible, but was discounted by the European Food Safety Authority in 2004 based on new evidence. This allowed the derivation of
Shota Morimoto et al.
Chemical communications (Cambridge, England), 49(18), 1811-1813 (2013-01-26)
A photo-switchable fluorescent flagging approach has been developed to identify photoaffinity-labeled peptides in target protein. Upon photochemical release of the ligand, the protein was newly modified with a coumarin in place of the previously attached biotin. It allowed us to
Shigehiro Sumiya et al.
The journal of physical chemistry. A, 117(7), 1474-1482 (2013-01-25)
A coumarin-amide-dipicolylamine linkage (L) was synthesized and used as a fluorescent receptor for metal cations in water. The receptor dissolved in water with neutral pH shows almost no fluorescence due to the photoinduced electron transfer (PET) from the amide and
María E Riveiro et al.
Bioorganic & medicinal chemistry, 17(18), 6547-6559 (2009-09-01)
The presumption that some coumarins might be lead compounds in the search for new differentiation agents against leukemia is based on the fact that natural coumarins, 5-(3-methyl-2-butenyloxy)-6,7-methylenedioxycoumarin (C-2) and 5-methoxy-6,7-methylenedioxycoumarin (C-1) inhibit proliferation and induce differentiation in U-937 cells [Riveiro

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