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Merck
CN

C3652

5α-胆甾-7-烯-3β-醇

别名:

3β-羟基-5α,7-胆甾烯, 烯胆甾烷醇

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关于此项目

经验公式(希尔记法):
C27H46O
化学文摘社编号:
分子量:
386.65
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
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InChI

1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h10,18-21,23-25,28H,6-9,11-17H2,1-5H3/t19-,20+,21?,23?,24?,25?,26?,27?/m1/s1

SMILES string

CC(CCC[C@@H](C)[C@@](CC[C@]1(C2=CC[C@@]3([H])C[C@@](O)(CC[C@]43C)[H])[H])([C@]1(CC[C@@]24[H])C)[H])C

InChI key

IZVFFXVYBHFIHY-IRRCOBOTSA-N

assay

≥98% (TLC)

form

powder

shipped in

ambient

storage temp.

−20°C

Quality Level

Application

5α-胆甾-7-烯-3β-醇被用作酶法测定血浆胆固醇的底物。它还被作为饲料添加剂,以研究其对 盔型溞 生活史性状的影响。

Biochem/physiol Actions

5α-胆甾-7-烯-3β-是胆固醇生物合成途径的中间体。血清中的甾醇由脂蛋白携带,并指示胆固醇合成速率。它作为胆固醇合成的标记物,不受饮食摄入胆固醇的影响。

Preparation Note

5α-胆甾-7-烯-3β-醇在氯仿中生成澄清、无色溶液,浓度为 10 mg/mL。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Artyom Kopp
Current biology : CB, 22(23), R1004-R1006 (2012-12-12)
Host-plant specialization plays a key role in insect evolution, but little is known about its molecular basis. A new paper shows that a cactus-feeding fly became restricted to its host by changes in an enzyme that converts dietary sterols into
Y H Han et al.
Biological & pharmaceutical bulletin, 23(10), 1247-1249 (2000-10-21)
From the butanol fraction of the starfish Asterina pectinifera Müler et Troschel (Asteriidae), we have isolated a new component, 5alpha-cholest-7-en-3beta-ol. Its antigenotoxic and antimutagenic activities were examined by the SOS chromotest with Escherichia coli PQ37 and by Ames test with
Matthew G K Benesch et al.
Biochemistry, 50(46), 9982-9997 (2011-09-29)
We performed differential scanning calorimetry (DSC) and Fourier transform infrared (FTIR) spectroscopic measurements to study the effects of lathosterol (Lath) on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine (DPPC) bilayer membranes and compared our results with those previously reported
Dominik Martin-Creuzburg et al.
Journal of chemical ecology, 30(3), 483-500 (2004-05-14)
In crustaceans, cholesterol is an essential nutrient, which they must directly obtain from their food or by bioconversion from other dietary sterols. Eukaryotic phytoplankton contain a great variety of sterols that differ from cholesterol in having additional substituents or different
A Besga et al.
Neuroscience letters, 510(2), 121-126 (2012-01-28)
Investigate possible associations of white matter hyperintensities (WMHs) with the metabolism of cholesterol and insulin in two subgroups of patients with memory complaints and different CSF Aβ42 and CSF tau levels. 59 patients from the memory clinic at Karolinska Hospital

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