所有图片(2)
About This Item
经验公式（希尔记法）:
C27H46O
CAS号:
分子量:
386.65
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.77
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方案
≥98% (TLC)
质量水平
表单
powder
运输
ambient
储存温度
−20°C
SMILES字符串
CC(CCC[C@@H](C)[C@@](CC[C@]1(C2=CC[C@@]3([H])C[C@@](O)(CC[C@]43C)[H])[H])([C@]1(CC[C@@]24[H])C)[H])C
InChI
1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h10,18-21,23-25,28H,6-9,11-17H2,1-5H3/t19-,20+,21?,23?,24?,25?,26?,27?/m1/s1
InChI key
IZVFFXVYBHFIHY-IRRCOBOTSA-N
应用
5α-胆甾-7-烯-3β-醇被用作酶法测定血浆胆固醇的底物。它还被作为饲料添加剂，以研究其对 盔型溞 生活史性状的影响。
生化/生理作用
5α-胆甾-7-烯-3β-是胆固醇生物合成途径的中间体。血清中的甾醇由脂蛋白携带，并指示胆固醇合成速率。它作为胆固醇合成的标记物，不受饮食摄入胆固醇的影响。
制备说明
5α-胆甾-7-烯-3β-醇在氯仿中生成澄清、无色溶液，浓度为 10 mg/mL。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
G S Tint et al.
Journal of lipid research, 15(3), 256-262 (1974-05-01)
The metabolism of Delta(7)-cholestenol, cholesterol, and cholestanol was examined in a patient with cerebrotendinous xanthomatosis after intravenous pulse-labeling with a mixture of dl-[2-(14)C]mevalonate and stereospecific 3S,4S,3R,4R-[4-(3)H]mevalonate. Silver nitrate and reversed-phase thin-layer chromatography were used to purify the sterols isolated from
Dominik Martin-Creuzburg et al.
Journal of chemical ecology, 30(3), 483-500 (2004-05-14)
In crustaceans, cholesterol is an essential nutrient, which they must directly obtain from their food or by bioconversion from other dietary sterols. Eukaryotic phytoplankton contain a great variety of sterols that differ from cholesterol in having additional substituents or different
W C Duane
Journal of lipid research, 36(2), 343-348 (1995-02-01)
We measured serum lathosterol levels and whole body cholesterol synthesis by sterol balance in 12 human subjects on a metabolic ward in four randomly allocated, 6-7 week periods: 1) lovastatin (40 mg b.i.d.) + low cholesterol diet (mean 246 mg/day);
A Rahier
Biochemistry, 40(1), 256-267 (2001-01-05)
Deuterium-labeled 5alpha-cholest-7-en-3beta-ol (1) bearing one or two deuteriums at the C-5alpha and (or) C-6alpha positions was synthesized in high isotopic and chiral purity. These compounds were used as substrates with the microsomal wild-type Zea mays and recombinant Arabidopsis thaliana Delta(7)-sterol-C5(6)-desaturases
Artyom Kopp
Current biology : CB, 22(23), R1004-R1006 (2012-12-12)
Host-plant specialization plays a key role in insect evolution, but little is known about its molecular basis. A new paper shows that a cactus-feeding fly became restricted to its host by changes in an enzyme that converts dietary sterols into
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