产品名称
抗-霍乱毒素 兔抗, whole antiserum
biological source
rabbit
conjugate
unconjugated
antibody form
whole antiserum
antibody product type
primary antibodies
clone
polyclonal
contains
15 mM sodium azide
technique(s)
Ouchterlony double diffusion: 1:16
dot blot: 1:20,000
indirect ELISA: 1:8,000
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Application
兔抗霍乱毒素抗体可用于:
- 蛋白质印迹
- 神经节苷脂依赖性定量酶联免疫检测(ELISA)
- 双向免疫扩散
Biochem/physiol Actions
霍乱毒素(CT)是一种多功能蛋白,在免疫系统中起一定作用。它具有免疫调节、佐剂特性,还可以用作消炎药。其免疫调节特性可用于治疗多种自身免疫性疾病。CT是多功能蛋白的最佳模型之一。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
抗血清可与霍乱毒素反应,但与葡萄球菌肠毒素A和葡萄球菌肠毒素B和假单胞菌外毒素A(蛋白浓度:50-500 ng / dot)无反应。尚未检测本品对活性霍乱毒素的中和效力。
霍乱毒素是霍乱的病原体,由按照AB5的化学计量组装的两个亚基A(27 kDa)和B(12 kDa)组成。 B亚基可与位于肠上皮细胞膜中的特定受体单唾液酸神经节苷脂 GM1结合。A亚基的A1片段可改变位置穿过宿主细胞膜,并催化腺苷酸环化酶复合物的Gsa调节成分的ADP核糖基化。由此导致的循环AMP水平的增加促进了多种作用,包括肠上皮细胞氯离子的分泌。
Immunogen
霍乱弧菌毒素
Preparation Note
脱脂
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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