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经验公式(希尔记法):
C16H19ClN2 · C4H4O4
化学文摘社编号:
分子量:
390.86
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
204-037-5
MDL number:
产品名称
(±)-氯苯那敏 马来酸盐, ≥99% (perchloric acid titration)
InChI key
DBAKFASWICGISY-BTJKTKAUSA-N
InChI
1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
SMILES string
CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.O=C(/C=C\C(O)=O)O
assay
≥99% (perchloric acid titration)
form
powder
mp
130-135 °C (lit.)
originator
Bayer
Quality Level
Gene Information
human ... HRH1(3269)
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Application
(±)-马来酸氯苯吡胺已被用于:
- 作为H1受受体拮抗剂用于测定受体功能
- 阻断化合物48/80对血浆IGF-I的作用
- 作为标准品通过配有电位差计的顺序进样器用于快速感应和测定
Biochem/physiol Actions
H 1 组胺受体拮抗剂。
马来酸氯苯吡胺(CPM)可预防鼻炎和荨麻疹。它常用于治疗多种过敏症状。这种抗组胺药也用于小动物的兽医治疗。
General description
马来酸氯苯吡胺(CPM)/(3-(4-氯苯基)-N,N-二甲基-3-吡啶-2-基-丙烷-1-胺是一种烷基胺抗组胺药。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
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