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Merck
CN

C2542

Sigma-Aldrich

抗i-N-钙黏蛋白单克隆抗体 小鼠抗

clone GC-4, ascites fluid

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别名:
抗-A-CAM, 抗-A-细胞粘附分子
MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

ascites fluid

抗体产品类型

primary antibodies

克隆

GC-4, monoclonal

包含

15 mM sodium azide

种属反应性

chicken, mouse, human, rabbit, rat

技术

electron microscopy: suitable
immunohistochemistry (frozen sections): 1:100 using chicken cardiac muscle
microarray: suitable
western blot: 1:100 using chicken or rat cardiac muscle

UniProt登记号

应用

research pathology

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... CDH2(1000)
mouse ... Cdh2(12558)
rat ... Cdh2(83501)

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相关类别

一般描述

N-钙粘蛋白是一种钙依赖性细胞粘附分子,主要存在于癌细胞中。单克隆抗-N-钙黏蛋白抗体与脂肪细胞粘附分子(ACAM)胞外域的 N 端发生反应。

特异性

单克隆抗 N-钙粘蛋白抗体与人、小鼠、兔、鸡和大鼠中的 A-CAM 分子特异性反应。

免疫原

亲和纯化的鸡心 A-CAM。

应用

单克隆抗 N-钙黏蛋白抗体可用于免疫组化(1:100),以及作为蛋白质印迹的一抗(1:1000)。
单克隆抗 N-钙黏蛋白抗体可用于免疫荧光显微镜、电子显微镜和免疫印迹,研究细胞间粘附分子的受体定位。它也可以用于研究组织中粘附和相互作用的机制。

生化/生理作用

N-钙黏蛋白调节 Src 激酶途径,还促进细胞运动和侵袭。它抑制粘附连接形成,并破坏培养的晶状体细胞的已有的连接。

外形

小鼠单克隆抗 N-钙黏蛋白抗体以含有 15mM 叠氮化钠的腹水液形式提供。

储存及稳定性

需要连续使用时,可在 2-8℃ 下储存一个月。对于更长期的储存,溶液可以冷冻成工作等分试样。不建议重复冷冻和解冻。如果长期储存时出现轻微混浊,使用前通过离心澄清。

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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