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Merck
CN
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安全信息

C222

Sigma-Aldrich

Cathine hydrochloride

≥97.5% (HPLC), powder, anorexic

别名:

threo-2-Amino-1-hydroxy-1-phenyl propane hydrochloride, Pseudonorephedrine hydrochloride, S,S-Norpseudoephedrine hydrochloride

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About This Item

经验公式（希尔记法）:
C9H13NO · HCl
CAS号:
2153-98-2
分子量:
187.67
EC 号:
218-446-1
MDL编号:
MFCD00070245
UNSPSC代码:
12352200
PubChem化学物质编号:
24892476
NACRES:
NA.77

product name

Cathine hydrochloride,

形式

powder

质量水平

100

药品控制

USDEA Schedule IV; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

储存条件

desiccated

颜色

white to off-white

mp

172-175 °C

溶解性

H2O: 15 mg/mL, clear
0.1 M HCl: soluble
ethanol: soluble

应用

forensics and toxicology

SMILES字符串

Cl[H].C[C@H](N)[C@@H](O)c1ccccc1

InChI

1S/C9H13NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8;/h2-7,9,11H,10H2,1H3;1H/t7-,9+;/m0./s1

InChI key

DYWNLSQWJMTVGJ-DKXTVVGFSA-N

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生化/生理作用

Anorexic; with pharmacological effects similar to those of the amphetamines.

注意

Photosensitive

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302,H336

危险分类

Acute Tox. 4 Oral - STOT SE 3

靶器官

Central nervous system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

监管及禁止进口产品

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M B Ahmed et al.
Journal of ethnopharmacology, 39(3), 213-216 (1993-08-01)
Catha edulis is a plant that grows in certain areas of East Africa and the Arab Peninsula. The stimulating properties of fresh material were described more than seven centuries ago and today the habit of inducing a state of euphoria
E A Pehek et al.
Pharmacology, biochemistry, and behavior, 36(2), 267-271 (1990-06-01)
The effects of the psychostimulant (+)cathine (norpseudoephedrine) were examined in a two-choice, food-motivated, drug-discrimination paradigm. Rats were able to discriminate cathine from vehicle and this effect was dose- and time-dependent. Prior administration of cathine resulted in a diminished response (tolerance)
Raz Krizevski et al.
Journal of ethnopharmacology, 114(3), 432-438 (2007-10-12)
Khat (Catha edulis Forsk., Celastraceae) is a perennial shrub that was introduced to Israel by Yemenite immigrants. Khat young leaves are chewed as a stimulant. The main stimulating active principles in this plant are the phenylpropylamino alkaloids (-)-cathinone [(S)-alpha-aminopropiophenone], (+)-cathine
John S Chappell et al.
Forensic science international, 195(1-3), 108-120 (2009-12-29)
A primary concern with the forensic analysis of the khat plant (Catha edulis) has been the need to preserve the principle psychoactive component, cathinone, which converts to the less-active substance, cathine, after harvesting. The loss of cathinone has serious legal
Hyeon-Kyu Lee et al.
The Journal of organic chemistry, 77(12), 5454-5460 (2012-05-25)
Each of the enantiomers of both norephedrine and norpseudoephedrine were stereoselectively prepared from the common, prochiral cyclic sulfamidate imine of racemic 1-hydroxy-1-phenyl-propan-2-one by employing asymmetric transfer hydrogenation (ATH) catalyzed by the well-defined chiral Rh-complexes, (S,S)- or (R,R)-Cp*RhCl(TsDPEN), and HCO(2)H/Et(3)N as
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