DMT-2′O-Methyl-rC(ac) Phosphoramidite

生物来源

non-animal source (no BSE/TSE risk)

质量水平

300

产品线

Proligo Reagents

方案

≥99% (³¹P-NMR)
≥99.0% (reversed phase HPLC)

表单

powder

技术

oligo synthesis: suitable

杂质

≤0.1% single unspecified Impurity (reversed phase HPLC)
≤0.3% mC2 (reversed phase HPLC, Hydrolysate)
≤0.3% mC3 (reversed phase HPLC, DMT-rC(ac)me)
≤0.3% mC4 (reversed phase HPLC, DMT-rC(ac)me-Ac)
≤0.3% water content (Karl Fischer)
≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR)
≤1.0% mC1 (reversed phase HPLC, DMT-rC(ac)me-DMT)
≤3% residual Solvent content

颜色

white to off-white

λ

conforms (UV/VIS Identity)

适用性

conforms to structure for H-NMR
conforms to structure for LC-MS

相容性

configured for ABI

核苷分析

base: cytidine
base protecting group: acetyl
2' protecting group: methyl
5' protecting group: DMT
deprotection: standard

储存温度

2-8°C

SMILES字符串

P(N(C(C)C)C(C)C)(O[C@@H]1[C@H](O[C@H](C1OC)N5C=CC(=NC5=O)NC(=O)C)COC(c4ccc(cc4)OC)(c3ccc(cc3)OC)c2ccccc2)OCCC#N

InChI

1S/C42H52N5O9P/c1-28(2)47(29(3)4)57(54-26-12-24-43)56-38-36(55-40(39(38)52-8)46-25-23-37(44-30(5)48)45-41(46)49)27-53-42(31-13-10-9-11-14-31,32-15-19-34(50-6)20-16-32)33-17-21-35(51-7)22-18-33/h9-11,13-23,25,28-29,36,38-40H,12,26-27H2,1-8H3,(H,44,45,48,49)/t36-,38-,39?,40-,57?/m1/s1

InChI key

WNWUMIPFLOKTEZ-IXZONTHDSA-N