C1879
氯化胆碱
synthetic, ≥98%, Choline acetyltransferase substrate, powder or crystals
别名:
(2-羟乙基)三甲基氯化铵
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关于此项目
线性分子式:
(CH3)3N(Cl)CH2CH2OH
化学文摘社编号:
分子量:
139.62
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-655-4
MDL number:
Beilstein/REAXYS Number:
3563126
产品名称
氯化胆碱, ≥98%
Quality Level
form
powder or crystals
technique(s)
cell culture | mammalian: suitable
color
colorless to white
mp
302-305 °C (dec.) (lit.)
InChI key
SGMZJAMFUVOLNK-UHFFFAOYSA-M
InChI
1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
SMILES string
[Cl-].C[N+](C)(C)CCO
biological source
synthetic
assay
≥98%
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Application
氯化胆碱已用于：
- 作为使用荧光测定法测定胆碱氧化酶酶活性的底物
- 作为非生理缓冲液的组分用于检测基于钙的细胞色素 c 氧化酶的抑制作用
- 作为灌流液的组分用于研究空肠样品中的动脉压
Biochem/physiol Actions
用氯化胆碱处理萝卜籽可调节磷脂酰胆碱和磷脂酰乙醇胺的水平。它能产生保肝作用并调节基于甲基碳的代谢途径。
General description
氯化胆碱是维生素 B4、胆碱的合成形式，是一种常见的家禽饲料。
胆碱乙酰基转移酶底物
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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An investigation into the relationship between small intestinal fluid secretion and systemic arterial blood pressure in the anesthetized rat
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Physiological Reports, 3(5) (2015)
Effect of choline chloride on the lipid content and composition in the leaves of principal magnetically-oriented radish types
Novitskaya GV, et al.
Russian Journal of Plant Physiology, 51(3), 361-371 (2004)
Choline and methionine differentially alter methyl carbon metabolism in bovine neonatal hepatocytes
Chandler TL and White HM
PLoS ONE, 12(2), e0171080-e0171080 (2017)
Cytochrome c oxidase inhibition by calcium at physiological ionic composition of the medium: Implications for physiological significance of the effect
Vygodina T, et al.
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