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偶联物
FITC conjugate
质量水平
形式
lyophilized powder
分子量
~12 kDa
组成
Protein, ~20% Lowry
标记范围
~1.0 mol FITC per mol protein
储存温度
2-8°C
SMILES字符串
CCOc1ccccc1C(=O)Nc2ccc(Cl)c(c2)C(F)(F)F
InChI
1S/C16H13ClF3NO2/c1-2-23-14-6-4-3-5-11(14)15(22)21-10-7-8-13(17)12(9-10)16(18,19)20/h3-9H,2H2,1H3,(H,21,22)
InChI key
YDXZSNHARVUYNM-UHFFFAOYSA-N
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应用
Cholera Toxin B subunit-fluorescein isothiocyanate (FITC) conjugate has been used as a fluorescent tracer:
- to label distal cerebrospinal fluid-contacting neurons (dCSF-CNs) in lateral ventricles of rat
- to stain epididymal sperms of mice
- to stain peritoneal macrophages of mice
生化/生理作用
The cholera toxin B subunit is used for track tracing in neurological research, taking advantage of GM1 ganglioside binding and retrograde transport. Tissue culture cells treated with cholera toxin are not killed and tissues of animals do not become necrotic.
特点和优势
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
外形
Lyophilized powder containing Tris buffer salts, sodium chloride, sodium EDTA and sodium azide
分析说明
Activity measured by ELISA using ganglioside GM1 coated multiwell plates, rabbit anti-cholera toxin B subunit antibodies, and peroxidase-labeled goat anti-rabbit IgG as the second antibody. 50% saturation of binding was achieved with 0.01-1 μg of the cholera toxin B subunit-FITC conjugate per mL.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Inhalation - Aquatic Chronic 3
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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