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质量水平
无菌性
0.2 μm filtered
形式
liquid
浓度
100 mg/mL in ethanol/water
溶解性
H2O: 100 mg/mL
ethanol: 100 mg/mL
适用性
suitable for testing specifications (Bacteriostatic (cell type) E. Coli DH5a, result: pass)
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
作用机制
cell wall synthesis | interferes
运输
wet ice
储存温度
−20°C
SMILES字符串
CC1(C)S[C@@H]2[C@H](NC(=O)C(C(O)=O)c3ccccc3)C(=O)N2[C@H]1C(O)=O
InChI
1S/C17H18N2O6S/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25)/t9?,10-,11+,14-/m1/s1
InChI key
FPPNZSSZRUTDAP-UWFZAAFLSA-N
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一般描述
化学结构:β-内酰胺
应用
羧苄青霉素(Carbenicillin)可用于筛选氨苄青霉素抗性转化细胞。还可用于研究青霉素敏感的转肽酶在细胞壁生物合成中的作用。
生化/生理作用
其他说明
保持容器密闭，并置于干燥通风处。打开后的容器必须小心重新密封并保持直立以防止泄漏。
警示用语：
Danger
危险声明
危险分类
Flam. Liq. 3 - Resp. Sens. 1 - Skin Sens. 1
WGK
WGK 2
闪点(°F)
104.0 °F
闪点(°C)
40 °C
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
G N Rolinson
The Journal of antimicrobial chemotherapy, 41(6), 589-603 (1998-08-01)
For more than 40 years the author has been involved in research in the field of beta-lactam antibiotics. Much of this work was concerned with the development of the semisynthetic penicillins, following the isolation of the penicillin nucleus, 6-aminopenicillanic acid.
Andrea Brenna et al.
AMB Express, 4, 43-43 (2014-06-21)
Agrobacterium tumefaciens-mediated transformation is a powerful tool for reverse genetics and functional genomic analysis in a wide variety of plants and fungi. Tuber spp. are ecologically important and gastronomically prized fungi ("truffles") with a cryptic life cycle, a subterranean habitat
A J Wright
Mayo Clinic proceedings, 74(3), 290-307 (1999-03-25)
The penicillin family of antibiotics remains an important part of our antimicrobial armamentarium. In general, these agents have bactericidal activity, excellent distribution throughout the body, low toxicity, and efficacy against infections caused by susceptible bacteria. The initial introduction of aqueous
Maria Tomás et al.
Antimicrobial agents and chemotherapy, 54(5), 2219-2224 (2010-03-03)
Expression of ampC, oprD, mexA, mexC, mexE, and mexX was studied in 25 Pseudomonas aeruginosa isolates from cystic fibrosis patients, including 14 isolates of the Liverpool epidemic strain. Overexpressed mexA or ampC and reduced oprD were associated with beta-lactam resistance.
Kunihiko Nishino et al.
Antimicrobial agents and chemotherapy, 54(5), 2239-2243 (2010-03-10)
NlpE, an outer membrane lipoprotein, functions during envelope stress responses in Gram-negative bacteria. In this study, we report that overproduction of NlpE increases multidrug and copper resistance through activation of the genes encoding the AcrD and MdtABC multidrug efflux pumps
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