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Merck
CN

C1251

Sigma-Aldrich

(+)-儿茶素 水合物

≥98% (HPLC), powder

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别名:
(+)-儿茶精-3, (2R,3S)-2-(3,4-二羟基苯基)-3,4-二氢-1(2H)-苯并吡喃-3,5,7-三醇
经验公式(希尔记法):
C15H14O6 · xH2O
分子量:
290.27 (anhydrous basis)
Beilstein:
3595244
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥98% (HPLC)

形式

powder

颜色

yellow to yellow with tan cast

mp

175-177 °C (anhydrous) (lit.)

溶解性

ethanol: 50 mg/mL

储存温度

2-8°C

SMILES字符串

[H]O[H].O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3

InChI

1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1

InChI key

OFUMQWOJBVNKLR-NQQJLSKUSA-N

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一般描述

儿茶素是植物化学物质,在黑葡萄、桃子、草莓和蚕豆中含量丰富。儿茶素有各种形式,如儿茶素、表儿茶素、表儿茶素没食子酸酯、表焙儿茶素和表没食子儿茶素没食子酸酯。

应用

(+)-水合儿茶素已用于以下情形:
  • 作为多酚标准品,测定红葡萄酒副产物中的多酚总量
  • 作为添加剂,通过三重进料批量方法研究对体外甲烷生产和底物降解的效果
  • 作为底物,测定L. plantarum CECT 748T 14重组鞣酸酶对儿茶素的活性

生化/生理作用

一种植物来源的抗氧化性黄酮类化合物;自由基清除剂,可在各种生物系统中防止自由基介导的损伤。例如,在生理pH条件下,儿茶素可抑制羟基自由基介导的DNA链断裂。它还可以防止人体血浆氧化。它延迟了内源性脂溶性抗氧化剂的消耗并抑制脂质氧化。儿茶素还可以作为脂肪酸合酶的抑制剂。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Nutrition and Health Info Sheet: Catechins (2008)
S B Lotito et al.
Free radical biology & medicine, 24(3), 435-441 (1998-01-23)
Based on the recognized capacity of (+)-catechin (CTCH) to prevent free radical-mediated damage in different biological systems, its role in the protection of human plasma from oxidation was investigated. Samples of human blood plasma were incubated with 50 mM AAPH
Christine Ziegler et al.
Molecular microbiology, 78(1), 13-34 (2010-10-07)
Increases in the environmental osmolarity are key determinants for the growth of microorganisms. To ensure a physiologically acceptable level of cellular hydration and turgor at high osmolarity, many bacteria accumulate compatible solutes. Osmotically controlled uptake systems allow the scavenging of
J Ueda et al.
Archives of biochemistry and biophysics, 333(2), 377-384 (1996-09-15)
The reactivities of various antioxidative compounds including catechol derivatives and endogenous radical scavengers toward hydroxyl radical (.OH) were investigated by an electron spin resonance-spin trapping method, thiobarbituric acid method, and DNA strand scission assay. Hydroxyl radical was generated by both
Hadeer M Ezzat et al.
International journal of pharmaceutics, 565, 488-498 (2019-05-18)
Catechin hydrate is a phytopharmaceutical with promising anticancer effects but poor bioavailability. This study aimed to elaborate catechin loaded chitosan-tethered liposomes (chitosomes) to enhance catechin oral bioavailability. Nanocarriers were optimized via ethanol injection method followed by physicochemical, ex vivo and

商品

Fatty acid synthesis supports cancer cell proliferation, essential for membrane generation, protein modification, and bioenergetics.

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

实验方案

Protocol for HPLC Analysis of Flavonoids on Ascentis® RP-Amide

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